Results 111 to 120 of about 2,840,930 (329)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

The medium isn’t the message: Introducing a measure of adaptive virtual communication

open access: yesCogent Arts & Humanities, 2018
Media use can be considered as an integral part of virtual communication and thus of present-day human interaction. Nevertheless, research on media use and effects still largely relies on laboratory experiments, treating it as a stable input condition ...
Lisa Handke   +3 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Some aspects of estimators in analysis of variance Model II. [PDF]

open access: yes, 1971
It is well known that the standard estimator for variance components in analysis of variance, Model II, can be a negative with positive probability. In practice, when such an estimator is found to be negative it is taken to be zero.
Green, Gary Allen
core  

Non-Additivity & Dependency In the Analysis of Variance [PDF]

open access: yesThe Egyptian Statistical Journal, 1975
Ibrahim M. Oweiss
doaj   +1 more source

Analysis of Molecular Variance (AMOVA) for Autopolyploids

open access: yesFrontiers in Ecology and Evolution, 2018
Autopolyploids present several challenges to researchers studying population genetics, since almost all population genetics theory, and the expectations derived from this theory, has been developed for haploids and diploids.
Patrick G. Meirmans, Shenglin Liu
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Welding Connection Strenght of Aluminium 1100 with Current Variations at Metal Inert Gas (MIG) Welding Process

open access: yesJurnal Energi Dan Manufaktur, 2012
In order to design of machine or building constructions use of welding connection, there are many factors should beconsidered such as skill, knowledge about welding procedures and material characteristics.
I Dewa Made Krishna Muku
doaj  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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