Results 121 to 130 of about 168,674,025 (284)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Resistance to change of responding maintained by unsignaled delays to reinforcement: a response-bout analysis.

open access: yes, 2006
Previous experiments have shown that unsignaled delayed reinforcement decreases response rates and resistance to change. However, the effects of different delays to reinforcement on underlying response structure have not been investigated in conjunction ...
Shahan, Timothy A.   +7 more
core   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Portfolio Selection with Monotone Mean-Variance Preferences [PDF]

open access: yes
We propose a portfolio selection model based on a class of monotone preferences that coincide with mean-variance preferences on their domain of monotonicity, but differ where mean-variance preferences fail to be monotone and are therefore not ...
Fabio Maccheroni   +3 more
core  

A Note on the asymptotic equivalence of jackknife and linearization variance estimation for the Gini Coefficient

open access: yes, 2008
The Gini coefficient has proved valuable as a measure of income inequality. In cross-sectional studies of the Gini coefficient, information about the accuracy of its estimate is crucial.
Berger, Yves G.
core   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

A new model for visualizing interactions in analysis of variance [PDF]

open access: yes
In analysis of variance, there is usually little attention for interpretingthe terms of the effects themselves, especially for interactioneffects. One of the reasons is that the number of interaction-effectterms increases rapidly with the number of ...
Koning, A.J., Groenen, P.J.F.
core  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Realized Variance and IID Market Microstructure Noise [PDF]

open access: yes
We analyze the properties of a bias-corrected realized variance (RV) in the presence of iid market microstructure noise. The bias correction is based on the first-order autocorrelation of intraday returns and we derive the optimal sampling frequency as ...
Asger Lunde, Peter Reinhard Hansen
core  

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