Results 11 to 20 of about 72,809 (223)
Some combinatorial identities related to commuting varieties and Hilbert schemes [PDF]
In this article we explore some of the combinatorial consequences of recent results relating the isospectral commuting variety and the Hilbert scheme of points in the ...
Ginzburg, V. +3 more
core +1 more source
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Matrix Groups: An Introduction to Lie Group Theory
Aimed at advanced undergraduate and beginning graduate students, this book provides a first taste of the theory of Lie groups as an appetiser for a more substantial further course.
Andrew Baker, Baker, Andrew, Baker, A.
core +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Heat kernels and Riesz transforms on nilpotent Lie groups [PDF]
We consider pure mth order subcoercive operators with complex coefficients acting on a connected nilpotent Lie group. We derive Gaussian bounds with the correct small time singularity and the optimal large time asymptotic behaviour on the heat kernel and
Elst, ter, A.F.M. +5 more
core
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
On extended structures in affine Toda field theory [PDF]
Two areas of affine Toda field theory are explored in this thesis. First the introduction of a boundary into the real coupling affine Toda field theory.
Harder, Ulrich Karl Priedrich
core

