Results 31 to 40 of about 72,809 (223)
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Random ergodic properties of some singular holomorphic foliations and Lie groups
Cette thèse s'intéresse à la théorie ergodique de certains systèmes dynamiques aléatoires. La première partie concerne l'étude de champs de vecteurs holomorphes sur l'espace projectif complexe avec un nombre fini de singularités, toutes hyperboliques. On
Lequen, Félix
core
Small RNA pathways in mammalian oocytes
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley +1 more source
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
Ternary structures in Hilbert spaces
PhDTernary structures in Hilbert spaces arose in the study of in nite dimensional manifolds in di erential geometry. In this thesis, we develop a structure theory of Hilbert ternary algebras and Jordan Hilbert triples which are Hilbert spaces equipped
Bahmani, Fatemeh
core
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
This thesis is written in the subfield of mathematics known as representation theory of real reductive Lie groups. Let G be a Lie group in the Harish-Chandra class with maximal compact subgroup K and Lie algebra g.
Analysis +2 more
core
Consistency of personality traits and verbal behaviour in leaderless small group discussion [PDF]
The research was concerned with consistency between three types of trait interaction and verbal behaviour in small student discussion groups. Hypotheses based on trait interactions of varying saliency were tested against samples of verbal behaviour ...
Halpin, Nicholas Richard, Halpin, N.R
core
ABSTRACT Background Accessing brain magnetic resonance imaging (MRI) can be challenging, especially for underserved patients, which may lead to disparities in neurological diagnosis. Method This mixed‐methods study enrolled adults with one of four neurological disorders: mild cognitive impairment or dementia of the Alzheimer type, multiple sclerosis ...
Maya L. Mastick +19 more
wiley +1 more source

