Results 91 to 100 of about 198,877 (319)

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

The θ-dependence of the Yang-Mills spectrum from analytic continuation

open access: yesJournal of High Energy Physics
We study the θ-dependence of the string tension and of the lightest glueball mass in four-dimensional SU(N) Yang-Mills theories. More precisely, we focus on the coefficients parametrizing the O θ 2 $$ \mathcal{O}\left({\theta}^2\right) $$ dependence of ...
Claudio Bonanno   +3 more
doaj   +1 more source

Analytic continuation and numerical evaluation of the kite integral and the equal mass sunrise integral

open access: yesNuclear Physics B, 2017
We study the analytic continuation of Feynman integrals from the kite family, expressed in terms of elliptic generalisations of (multiple) polylogarithms. Expressed in this way, the Feynman integrals are functions of two periods of an elliptic curve.
Christian Bogner   +2 more
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

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