Results 51 to 60 of about 309,134 (277)

Using the e-learning course “Analytic Geometry” in the process of training students majoring in Computer Science and Information Technology

CTE Workshop Proceedings, 2019
As a result of literature analysis the expediency of free access of bachelors majoring in Computer Sciences and Information Technologies to modern information educational resources, in particular, e-learning courses in the process of studying ...
Oksana M. Hlushak, Volodymyr V. Proshkin, Oksana S. Lytvyn   +2 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Proof of the Hyperplane Zeros Conjecture of Lagarias and Wang

, 2007
We prove that a real analytic subset of a torus group that is contained in its image under an expanding endomorphism is a finite union of translates of closed subgroups. This confirms the hyperplane zeros conjecture of Lagarias and Wang for real analytic
C. Andradas, D. Cerveau, E. Coven, E. Hewitt, E. Michael, E.R. Kamen van, E.R. Kampen van, H. Cartan, H. Grauert, H. Hironaka, H. Hironaka, H. Whitney, H.M.S. Smith, H.W. Turnbull, J. Dugundji, J. Frisch, J.C. Lagarias, J.L. Kelly, J.M.G. Fell, J.R. Munkres, K. Gröchenig, K. Hiraide, K. Hiraide, L.S. Pontryagin, L.S. Pontryagin, M. Gromov, M. Newman, R. Godement, R. Hartshorne, R. Kiehl, R. Narasimhan, S. Lojasiewicz, S.G. Krantz, W. Rudin, Wayne Lawton   +34 more
core   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Conformal Scalar Propagation on the Schwarzschild Black-Hole Geometry

, 2010
The vacuum activity generated by the curvature of the Schwarzschild black-hole geometry close to the event horizon is studied for the case of a massless, conformal scalar field.
B. Witt de, D.N. Page, G. Arfken, G.W. Gibbons, George Tsoupros, K.W. Howard, M.S. Fawcett, P. Candelas, P. Candelas, P.R. Anderson, P.R. Anderson, S.M. Christensen, S.W. Hawking   +12 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Secants of Abelian Varieties, Theta functions, and Soliton Equations

, 1996
This paper is a survey on relations between secant identities and soliton equations and applications of soliton equations to problems of algebraic geometry, i.e., the Riemann-Schottky problem and its analogues.
Taimanov, I. A.
core   +2 more sources

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Polarization-Blind Image Dehazing Algorithm Based on Joint Polarization Model in Turbid Media

Applied Sciences
To address the issue of reduced image contrast and visibility caused by turbid media, such as dense fog, this paper proposes a novel polarization-based single-image dehazing model.
Zhen Wang, Zhenduo Zhang, Rui Ma, Xueying Cao   +3 more
doaj   +1 more source

Multi-matrix models and emergent geometry

, 2008
Encouraged by the AdS/CFT correspondence, we study emergent local geometry in large N multi-matrix models from the perspective of a strong coupling expansion.
B. Craps, D. Berenstein, D. Berenstein, D. Berenstein, D. Berenstein, D.E. Berenstein, D.E. Berenstein, David E Berenstein, G. Ishiki, H.-Y. Chen, J. Ambjørn, J. Polchinski, J.M. Maldacena, L.L. Chau, Masanori Hanada, O. Aharony, P. Austing, P. Austing, R.C. Myers, S. Catterall, S.-J. Rey, Sean A Hartnoll, T.J. Hollowood, U. Gursoy, W. Krauth   +24 more
core   +1 more source