Results 101 to 110 of about 4,000,280 (256)
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Versatile vector tools for efficient protein screening across multiple expression systems
FEBS Open Bio, EarlyView.A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu +5 more
wiley +1 more source
REDUCTION NUMBERS AND IDEALS OF ANALYTIC SPREAD ONE
, 1986 Let (R,M) be a commutative Noetherian local ring having an infinite residue field and suppose I is an ideal in R. The reduction number of I (denoted r(I)) is defined, and conditions on R which force r(I) (LESSTHEQ) 1 for every regular analytic spread one
HUCKABA, SAM WAYNE
core
, 2018 Let (R, 𝔪) be a Noetherian local ring and I an arbitrary ideal of R with analytic spread s. In [3] the authors proved the existence of a chain of ideals I ⊆ I[s] ⊆ ⋅⋅⋅ ⊆ I[1] such that deg(PI[k]/I) < s − k.
V. H. JORGE PÉREZ +2 more
core +1 more source
FEBS Open Bio, EarlyView.The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley +1 more source
Partial normalizations of coxeter arrangements and discriminants [PDF]
, 2012 We study natural partial normalization spaces of Coxeter arrangements and discriminants and relate their geometry to representation theory. The underlying ring structures arise from Dubrovin’s Frobenius manifold structure which is lifted (without unit)
Mond, D. (David) +3 more
core
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
FEBS Open Bio, EarlyView.Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
Real nullstellensatz and *-ideals in *-algebras
, 2015 For a fixed tuple of square matrices X ={X_1,...,X_g} the set I(X) of all noncommutative polynomials p in X and X∗ such that p(X) = 0 is an ideal in the ∗-algebra of all polynomials. This article concerns such zeroes and their corresponding ideals.
Cimpric, J. +4 more
core +1 more source
FEBS Open Bio, EarlyView.TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose +9 more
wiley +1 more source
Equimultiple coefficient ideals
, 2017 Let $(R,\mathfrak {m})$ be a quasi-unmixed local ring and $I$ an equimultiple ideal of $R$ of analytic spread $s$. In this paper, we introduce the equimultiple coefficient ideals. Fix $k\in \{1,\dots ,s\}$. The largest ideal $L$ containing $I$ such that $
P. H. Lima, V. H. Jorge Pérez
core +2 more sources