Results 81 to 90 of about 652,083 (267)

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

ON DECRIPTIONS OF CLOSED IDEALS OF ANALYTIC AREA NEVANLINNA TYPE CLASSES IN A CIRCULAR RING ON A COMPLEX PLANE C

open access: yesПроблемы анализа, 2012
We define certain new large area Nevanlinna type spaces in circular ring K on a complex plane and provide complete decriptions of ideals of these new scales of spaces. Our results extend some previously known assertions.
SHAMOYAN R.F.
doaj  

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Constructing Nursing Professional Identity in Impossible Situations: A Longitudinal Narrative Study of New Nurses’ Transition to Practice

open access: yesGlobal Qualitative Nursing Research
Newly graduated nurses are expected to develop a strong professional identity during transition to practice, yet considerable research describes a gap between the ideals taught in nursing school and the realities of clinical work.
Laura L. Reilly, Shira Birnbaum
doaj   +1 more source

Notes on Number Theory

open access: yesMathematics
This paper presents a set of survey-style notes linking core themes of pure algebra with central topics in algebraic and analytic number theory. We begin with finite extensions of Q and describe algebraic number fields through their realization as finite-
Miroslav Stoenchev   +2 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

[Letter from Ideals Publishing Company to T. N. Carswell]

open access: yes, 1958
A letter written to Mr. T. N. Carswell, Abilene, Texas, from Ideals Publishing Co., Milwaukee 1, Wisconsin.
Ideals Publishing Company
core   +3 more sources

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