Results 91 to 100 of about 3,517,351 (323)
Demystifying the discharge coefficient for flow over thin weirs and sills
FlowA revised derivation of the discharge coefficient for flows over thin weirs and sills in the limits of wall overflow to a free overfall is given. Using dimensional analysis, we show that the discharge coefficient, $C_{d}$ , in the classical weir ...
Joseph E. Pugh +2 more
doaj +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Tip leakage flow structure and cavitation inception in a ducted marine propeller
FlowCavitation inception and the associated flow structure in the tip region of a ducted propeller are investigated experimentally at varying advance ratios (J) using high-speed imaging and stereoscopic particle image velocimetry (SPIV) measurements in a ...
Ayush Saraswat +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Applied Operations and AnalyticsThis article proposes a constructivist framework to support decision-making in the prioritization of training and development (T&D) project portfolios in a company in the oil, gas, and energy sector that adopts agile practices capable of prioritizing ...
Pedro Henrique Pierezan +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
A bodner-partom visco-plastic dynamic sphere benchmark problem [PDF]
, 2013 Developing benchmark analytic solutions for problems in solid and fluid mechanics is very important for the purpose of testing and verifying computational physics codes. Our primary objective in this research is to obtain a benchmark analytic solution to
Brock, Jerry S. +2 more
core
Thermally driven cross-shore flows in stratified basins: a review on the thermal siphon dynamics
FlowThe sloping boundaries of stratified aquatic systems, such as lakes, are crucial environmental dynamic zones. While the role of sloping boundaries as energy dissipation hotspots is well established, their contribution to triggering large-scale motions ...
Damien Bouffard +3 more
doaj +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Applied Operations and AnalyticsThe growing demand for convenience in the food industry has increased the fast-food restaurant (FFR) market. Key factors like order speed and accuracy, reinforced by technological advancements like self-service kiosks (SSK), shape overall service quality
C. C. Cuento +3 more
doaj +1 more source