Results 101 to 110 of about 14,862 (292)

Unveiling mysteries of micro-porous structures in xylem vascular of plants: characterising nutrient transport using electro-hydrodynamics

Flow
We unveil the flow and ionic transport characteristics of xylem vessels to establish a correlation between in situ electrical energy generation and plant bioregulation.
Jinmay Kalita, Sumit Kumar Mehta, Pranab Kumar Mondal   +2 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

A semi-analytic method for crack kinking analysis at isotropic bi-material interfaces [PDF]

, 2012
Interface delamination is a key failure mechanism in numerous applications. Microscopic analysis illustrates that macroscopic delamination may contain both adhesive and cohesive cracking.
O. van der Sluis, Sluis, van der, O.; id_orcid, Zhang, G.Q., Sluis, van der, O., Noijen, S.P.M., G.Q. Zhang, S.P.M. Noijen, P.H.M. Timmermans, Timmermans, P.H.M.   +8 more
core   +1 more source

A novel ultra-high-speed air-based Taylor–Couette apparatus for exploring narrow-gap flows in high-speed rotating machinery

Flow
We present the design, construction and initial experimental validation of the Northwestern Polytechnical University Taylor–Couette (NPU-TC) apparatus, specifically developed to explore turbulent Taylor–Couette flows under conditions relevant to ultra ...
Xi-Ran Liu, Xue-Jie Wang, Jia-Qi Ma, Xin Chen, Heng-Dong Xi   +4 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Physical and celestial mechanics, in four systems. [PDF]

v.1. Analytic mechanics--v.2. Celestial mechanics--v.3. Potential physics--v.4.
Peirce, Benjamin, 1809-1880.
core  

Systematic study on the mechanical and electric behaviors of the nonbuckling interconnect design of stretchable electronics [PDF]

, 2018
Recently, we developed a nonbuckling interconnect design that provides an effective approach to simultaneously achieving high elastic stretchability, easiness for encapsulation, and high electric performance for stretchable electronics.
Liu, Hao, Guo, Xu, Wu, HuaPing, Li, Rui, Chen, YuLi, Zhang, Han, Hu, JianQiao, Ping, XueCheng, Huang, MingQi, Xue, RiYe, Su, YeWang   +10 more
core   +1 more source

Vortices produced by swirl-mixing grids in nuclear fuel assembly: a wind-tunnel experiment

Flow
Longitudinal vortices produced by a swirl-mixing grid are experimentally explored in an upscaled model of nuclear fuel assembly. The flow is mapped using particle image velocimetry in several planes downstream of the grid.
Matěj Dolejš, Daniel Duda, Vojtěch Janský, Anna Mrázová, Václav Uruba, Vitalii Petrovych Yanovych, Ingrid Karoline Vasconcelos da Silva, Kateryna Viktorivna Kovalova   +7 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Resistance to digital transition: a literature review

Applied Operations and Analytics
This study explores factors associated with resistance to digital transition in organizations, a phenomenon that has received increasing attention in recent years.
Sérgio Lopes Resende, Gonçalo Paiva Dias, Pedro Alves Correia   +2 more
doaj   +1 more source