Results 71 to 80 of about 1,113,738 (296)
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Mechanics of non-holonomic systems: a new class of control systems
, 2009 Mechanics of non-holonomic systems gives a deep insight into the theory and applications of Analytical Mechanics. The theory suggested is illustrated by the examples of a spacecraft motion.
IUshkov, M P +2 more
core
Quantum Mechanics With Application
, 2011 The ebook introduces undergraduate students to the basic skills required to use non-relativistic quantum mechanics for bound and scattering problems in atomic, molecular and nuclear physics.
Iraj R. Afnan
core +1 more source
Dynamics of turbulent flow over mobile dune
FlowThe present study reveals the turbulence dynamics and morphological adjustments of mobile dune-shaped bedforms in an alluvial stream. Results demonstrate acceleration of flow over the dune crest enhancing streamwise velocity, while the initial and the ...
Pradyumna Kumar Behera +2 more
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
FlowBase-flow computations and stability analyses are performed for a hypersonic wind tunnel nozzle at a Mach number of 6. Isothermal and adiabatic wall boundary conditions are investigated, and moderate stagnation conditions are used to provide ...
Hugo Lemarquand +5 more
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Data-driven modelling for on-demand flow prescription in fan-array wind tunnels
FlowFan-array wind tunnels are an emerging technology to prescribe wind fields through grids of individually controllable fans. This design is especially suited for the turbulent, dynamic, non-uniform flow conditions found close to the ground, and has ...
Alejandro Stefan-Zavala +4 more
doaj +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
2019 Summer Aerospace Engineering & Mechanics Newsletter
, 2019 Aerospace Engineering & Mechanics. (2019). 2019 Summer Aerospace Engineering & Mechanics Newsletter.
Aerospace Engineering & Mechanics
core