Results 61 to 70 of about 1,113,738 (296)
FlowWe provide a unified theory, within the framework of the multi-phase Darcy description, on gravity current, interfacial and unsaturated flows in a vertically heterogeneous porous layer, which finds applications in many geophysical, environmental and ...
Zhong Zheng
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
CFD prediction and experimental visualisation of cavitation and its erosion in hydraulic valves
FlowThis article presents an experimentally validated computational fluid dynamics (CFD) model for localising and quantifying cavitation erosion in oil hydraulic valves using large eddy simulation (LES) turbulence modelling and the cavitation erosion indices
Sven Osterland, Jürgen Weber
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Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
FlowIn this study, the method of large-eddy simulation (LES) is applied to investigate the impact of patches of coarsened riverbed sediments on near-bed hydrodynamics and flow resistance. Six simulations are performed with riverbed coverage ratios of coarser
Jiangchao Liu +4 more
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Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
FlowAs a novel type of catalytic Janus micromotor (JM), a double-bubble-powered Janus micromotor has a distinct propulsion mechanism that is closely associated with the bubble coalescence in viscous liquids and corresponding flow physics. Based on high-speed
Leilei Wang +7 more
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Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
, 2011 : We discuss fundamentals of the covariant analytic mechanics with differential forms. We apply it to typical field theories, such as a scalar field, the electromagnetic field, and a non-abelian gauge field, as well as the Newtonian mechanics of a ...
Yasuhito Kaminaga
core
Assessment of mixing efficiency of thermally driven microfluidic swirlers
FlowIn this study, we examine the mixing performance of thermally induced microfluidic swirlers, which are recently developed micromixers based on mixed thermal convection.
Filippo Azzini +6 more
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