Results 51 to 60 of about 31,677 (264)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Comparative Analysis between Fuzzy and Traditional Analytical Hierarchy Process

open access: yesMATEC Web of Conferences, 2014
Analytic Hierarchy Process (AHP) is one of the techniques commonly used for prioritizing different alternatives, by using complex criteria. In real applications, conventional AHP assumes the expert judgment as it is exact and use crisp number leading to ...
Mulubrhan Freselam   +2 more
doaj   +1 more source

Selecting equipment using a hybrid of AHP and PROMETHEE [PDF]

open access: yesManagement Science Letters, 2013
, Pages 1767-1772 and PDF (194 K)Abstract: Having appropriate technology is an important managerial decision in today’s manufacturing industry and to choose a good technology, we need to consider various alternatives.
Mohammad Sadegh Horri, Porya Moradi
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Quantitative analytical hierarchy process to marketing store location selection

open access: yesMATEC Web of Conferences, 2018
The selection of Store to market the product is belong to Multi Criteria Decision Making problem. The criteria used have conflict of interest with each other to produce an optimal location.
Harwati, Utami Intan
doaj   +1 more source

IMPLEMENTATION OF AHP METHOD IN THE DECISION SUPPORT OF SELECTION OF STUDENT ACHIEVEMENT CASE STUDY: SENIOR HIGH SCHOOL

open access: yesJurnal Riset Informatika, 2020
The research to look for excellence that each student has in order to find out students who excel. Through academic and non-academic achievements can be a benchmark for finding the best students.
Ari Puspita   +3 more
doaj   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

A Clarification of “Remarks on the Analytic Hierarchy Process” [PDF]

open access: yesManagement Science, 1990
The replies by Saaty (1990) and by Harker and Vargas (1990) to my remarks on the Analytic Hierarchy Process (Dyer 1990) are useful in focusing attention on areas of disagreement regarding the AHP, and provide readers with sufficient information to form their own opinions.
openaire   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

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