Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
Molecular Oncology, EarlyView.The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias +12 more
wiley +1 more source
Fundamentals and Applications of Fluid Mechanics and Acoustics in Biomedical Engineering
BioengineeringThe field of biomedical engineering has experienced important recent advances in experimental, computational, and analytical research in fluid mechanics and acoustics [...]
Iris Little, Ephraim Gutmark
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Cross-Coupled Heat and Moisture Transport Part 2/1: Applications in Mechanics
Journal of Mechanical Engineering, 2018 Based on the theory laid down in the Part 1 [1] in this paper we are going to display applications in physics and especially in mechanics. After a short summary on coupled fields in mechanics, we generally analyze the analogies in mechanics.
Andras Szekeres, Balazs Fekete
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Molecular Oncology, EarlyView.TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach +8 more
wiley +1 more source
Thirring: DIE GESCHICHTE DER ATOMBOMBE/de Broglie: L'OPTIQUE ELECTRONIQUE/Slater: MICROWAVE TRANSMISSION/Lindsay: AN INTRODUCTION TO PHYSICAL STATISTICS/Bergmann: INTRODUCTION TO THE THEORY OF RELATIVITY/Reichenbach: PHYLOSOPHIC FOUNDATIONS OF QUANTUM MECHANICS/Bridgman: THE NATURE OF THERMODYNAMICS/Dunning und Paxton: MATTER, ENERGY, AND RADIATION/Fermi: NUCLEAR PHYSICS/Lemon und Ferrence: ANALYTICAL EXPERIMENTAL PHYSICS/Gamow: THE BIRTH AND DEATH OF THE SUN/„DER ANFANG ODER DAS ENDE?”︁ [PDF]
, 1947 Geschichte Die +2 more
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Molecular Oncology, EarlyView.A DIA‐MS‐based proteomics analysis of serum samples from GB patients and healthy controls showed that high levels of IL1R2 and low levels of CRTAC1 and HRG in serum are associated with poor survival outcomes for GB patients. These circulating proteins could serve as biomarkers for the prediction of outcome in patients with GB.
Anne Clavreul +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon +13 more
wiley +1 more source
Analytical mechanics and almost vibrationally-adiabatic chemical reactions [PDF]
, 1967 R. A. Marcus
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Molecular Oncology, EarlyView.Raphin‐1 reduces the survival of PED‐DHGG cells and enhances their radiation sensitivity through both PeIF2α‐dependent and PeIF2α‐independent mechanisms. Raphin‐1 sustains elevated levels of PeIF2α, contributing to its PeIF2α‐dependent effects. Additionally, raphin‐1 interacts with CReP to mediate a separate radiosensitizing pathway that operates ...
Karin Eytan +4 more
wiley +1 more source
Geometric nonlinearities in field theory, condensed matter and analytical mechanics
Condensed Matter Physics, 2010 There are two very important subjects in physics: Symmetry of dynamical models and nonlinearity. All really fundamental models are invariant under some particular symmetry groups.
J.J. Sławianowski
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