Results 91 to 100 of about 3,321,873 (370)

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

Retrieving information from a noisy "knowledge network"

open access: yes, 2007
We address the problem of retrieving information from a noisy version of the ``knowledge networks'' introduced by Maslov and Zhang. We map this problem onto a disordered statistical mechanics model, which opens the door to many analytical and numerical ...
Castellani T, J Barré, Montanari A
core   +1 more source

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

open access: yesMolecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh   +8 more
wiley   +1 more source

Theoretical analysis of transverse impact response in double layer graphene sheets

open access: yesAIP Advances, 2016
In designing future nanoscale devices or nanostructures as new element in structural mechanics, it is very important to predict the responses for these elements against various mechanical loading conditions.
Toshiaki Natsuki, Qing-Qing Ni
doaj   +1 more source

Analyzing the Motion of Symmetric Tops Without Recurring to Analytical Mechanics

open access: yesFrontiers in Physics, 2020
Characterizing the dynamics of heavy symmetric tops is essential in several fields of theoretical and applied physics. Accordingly, a series of approaches have been developed to describe their motion.
Zsolt I. Lázár   +3 more
doaj   +1 more source

Analytical solution of stochastic model of risk-spreading with global coupling

open access: yes, 2013
We study a stochastic matrix model to understand the mechanics of risk-spreading (or bet-hedging) by dispersion. Such model has been mostly dealt numerically except for well-mixed case, so far.
Morita, Satoru, Yoshimura, Jin
core   +1 more source

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

open access: yesMolecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton   +17 more
wiley   +1 more source

Mechanics Property Analysis of High-resistance Steel Wire Mesh in Slope Flexible Stabilization System

open access: yesChemical Engineering Transactions, 2015
This paper aims at studying deformation mechanism and mechanics property of high-resistance steel wire mesh in slope flexible stabilization system and makes theoretical analysis under unilateral tension, and the analytical results are compared with the ...
G.S. Wang, S.Q. Shi, M. Wang
doaj   +1 more source

Jacobi Elliptic Functions and the Complete Solution to the Bead on the Hoop Problem

open access: yes, 2012
Jacobi elliptic functions are flexible functions that appear in a variety of problems in physics and engineering. We introduce and describe important features of these functions and present a physical example from classical mechanics where they appear: a
Baker, Thomas E., Bill, Andreas
core   +1 more source

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