Results 91 to 100 of about 515,471 (330)
Study of Contact Parameters in Metal-On-Plastic Hip Endoprosthesis with the Analytical-Numerical Method of Contact Mechanics [PDF]
, 2023 Myron Chernets, Jarosław Zubrzycki
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Contact area of rough spheres: Large scale simulations and simple scaling laws
, 2016 We use molecular simulations to study the nonadhesive and adhesive atomic-scale contact of rough spheres with radii ranging from nanometers to micrometers over more than ten orders of magnitude in applied normal load. At the lowest loads, the interfacial
Bowden F. P. +5 more
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Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
On the methods of analytical mechanics for mathematical modeling of the dynamics of non-free systems and some variants of their application to the dynamics of parallel manipulators [PDF]
, 2022 Aleksandr Ya. Krasinskiy
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Advanced algorithm for orbit computation [PDF]
Computational and analytical techniques which simplify the solution of complex problems in orbit mechanics, Astrodynamics and Celestial Mechanics were developed.
Szenbehely, V.
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Self-Similar Crossover in Statistical Physics
, 2000 An analytical method is advanced for constructing interpolation formulae for complicated problems of statistical mechanics, in which just a few terms of asymptotic expansions are available.
Baker +34 more
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Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Analytical and numerical relaxation results for models in soil mechanics [PDF]
, 2022 Klaus Hackl +3 more
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Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Jacobi Elliptic Functions and the Complete Solution to the Bead on the Hoop Problem
, 2012 Jacobi elliptic functions are flexible functions that appear in a variety of problems in physics and engineering. We introduce and describe important features of these functions and present a physical example from classical mechanics where they appear: a
Baker, Thomas E., Bill, Andreas
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