Results 71 to 80 of about 41,264 (251)

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Analytical mechanics solution for measuring the deflection of strengthened RC beams using FRP plates

Case Studies in Construction Materials, 2019
Partial-interaction due to sliding between the steel bars, adhesively attached FRP plates and their bordering concrete surface, accompanied with the detachment of the FRP plates due to intermediate crack (IC) debonding make the deflection of strengthened
Mohamed El-Zeadani, Raizal Saifulnaz M.R., Y.H. Mugahed Amran, F. Hejazi, M.S. Jaafar, Rayed Alyousef, Hisham Alabduljabbar   +6 more
doaj   +1 more source

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

FEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual, Marta Navarro‐Gutiérrez, Verónica Romero‐Albillo, Raquel Jiménez‐Sánchez   +3 more
wiley   +1 more source

Neural network-based snow depth retrieval from AMSR-2 brightness temperatures using ICESat-2 measurement as ground truth

Frontiers in Remote Sensing
IndroductionEstimating snow depth over Arctic sea ice is essential for understanding climate processes and supporting operational forecasting. Previous work has demonstrated the use of lidar backscattering pathlength moments from Ice, Cloud, and land ...
Sunny Sun-Mack, Yongxiang Hu, Xiaomei Lu, Yan Chen, Ali Omar   +4 more
doaj   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

FEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park, Inho Kwon, Yong Hwan Kim, Ji‐Eun Bae, Joon Bum Kim, Seong Hyun Kim, Sungho Maeng, Doo Sin Jo, Dong‐Hyung Cho   +8 more
wiley   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Mechanics Property Analysis of High-resistance Steel Wire Mesh in Slope Flexible Stabilization System

Chemical Engineering Transactions, 2015
This paper aims at studying deformation mechanism and mechanics property of high-resistance steel wire mesh in slope flexible stabilization system and makes theoretical analysis under unilateral tension, and the analytical results are compared with the ...
G.S. Wang, S.Q. Shi, M. Wang
doaj   +1 more source

How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome

FEBS Letters, EarlyView.
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini, Freia S. Buus, Benjamin Schuler, Birthe B. Kragelund   +3 more
wiley   +1 more source

Fundamentals and Applications of Fluid Mechanics and Acoustics in Biomedical Engineering

Bioengineering
The field of biomedical engineering has experienced important recent advances in experimental, computational, and analytical research in fluid mechanics and acoustics [...]
Iris Little, Ephraim Gutmark
doaj   +1 more source

Mechanisms of Lagrangian Analyticity in Fluids [PDF]

Archive for Rational Mechanics and Analysis, 2019
Certain systems of inviscid fluid dynamics have the property that for solutions that are only slightly better than differentiable in Eulerian variables, the corresponding Lagrangian trajectories are analytic in time. We elucidate the mechanisms in fluid dynamics systems that give rise to this automatic Lagrangian analyticity, as well as mechanisms in ...
openaire   +3 more sources