Results 71 to 80 of about 2,375,122 (290)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Towards a Group-Theoretical Interpretation of Mechanics [PDF]

open access: yes, 2013
We argue that the classical description of a symplectic manifold endowed with a Hamiltonian action of an abelian Lie group G and the corresponding quantum theory can be understood as different aspects of the unitary representation theory of G.
Catren, Gabriel
core  

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Neural network-based snow depth retrieval from AMSR-2 brightness temperatures using ICESat-2 measurement as ground truth

open access: yesFrontiers in Remote Sensing
IndroductionEstimating snow depth over Arctic sea ice is essential for understanding climate processes and supporting operational forecasting. Previous work has demonstrated the use of lidar backscattering pathlength moments from Ice, Cloud, and land ...
Sunny Sun-Mack   +4 more
doaj   +1 more source

The Analyst : The Journal of the Society for Analytical Chemistry

open access: yes, 1970
1048 hal,;ill,;27 ...
Society for Analytical Chemistry
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

How to Derive an Analytical Network Mechanics Theory [PDF]

open access: yes, 1998
This report was originally written as a part of the course material in the FPIRC course Paper Mechanics given at STFI/KTH. The aim of the report is to explain the ideas behind analytical network theories based on the homogeneous strain assumption in a ...
Heyden, Susanne
core  

On the Classical Limit of Quantum Mechanics [PDF]

open access: yes, 2008
Contrary to the widespread belief, the problem of the emergence of classical mechanics from quantum mechanics is still open. In spite of many results on the ¯h → 0 asymptotics, it is not yet clear how to explain within standard quantum mechanics the ...
Allori, Valia, Zanghi, Nino
core   +1 more source

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