Results 51 to 60 of about 41,264 (251)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

The ZX-calculus is incomplete for quantum mechanics [PDF]

Electronic Proceedings in Theoretical Computer Science, 2014
We prove that the ZX-calculus is incomplete for quantum mechanics. We suggest the addition of a new 'color-swap' rule, of which currently no analytical formulation is known and which we suspect may be necessary, but not sufficient to make the ZX-calculus
Christian Schröder de Witt, Vladimir Zamdzhiev   +1 more
doaj   +1 more source

Analytic continuation of stochastic mechanics [PDF]

Journal of Mathematical Physics, 2022
We study a (relativistic) Wiener process on a complexified (pseudo-)Riemannian manifold. Using Nelson’s stochastic quantization procedure, we derive three equivalent descriptions for this problem. If the process has a purely real quadratic variation, we obtain the one-sided Wiener process that is encountered in the theory of Brownian motion.
openaire   +2 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Regional Characterization of Deep Convective Clouds for Enhanced Imager Stability Monitoring and Methodology Validation

Remote Sensing
The NASA CERES project conducts an independent assessment of the calibration stability of MODIS and VIIRS reflective solar bands to ensure consistency in CERES-derived clouds and radiative flux products.
David Doelling, Prathana Khakurel, Conor Haney, Arun Gopalan, Rajendra Bhatt   +4 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Novel Analytical and Numerical Approximations to the Forced Damped Parametric Driven Pendulum Oscillator: Chebyshev Collocation Method

Journal of Mathematics, 2022
In this work, some novel approximate analytical and numerical solutions to the forced damped driven nonlinear (FDDN) pendulum equation and some relation equations of motion on the pivot vertically for arbitrary angles are obtained.
M.R. Alharthi, Alvaro H. Salas, Wedad Albalawi, S.A. El-Tantawy   +3 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Polarization calibration of spaceborne lidar using dense cirrus–scattered solar background with molecular scattering correction [PDF]

Atmospheric Measurement Techniques
Accurate calibration is essential for spaceborne polarization-sensitive lidars, as biases in depolarization ratio measurements can significantly affect the retrieval of cloud and aerosol properties.
Z. Liu, M. A. Vaughan, M. A. Vaughan, P. Zhai, A. E. Garnier, A. E. Garnier, S. Zeng, S. D. Rodier, S. D. Rodier, Y. Hu, A. H. Omar, C. R. Trepte   +11 more
doaj   +1 more source