Results 131 to 140 of about 3,655,467 (372)

NanoCMSer: a consensus molecular subtype stratification tool for fresh‐frozen and paraffin‐embedded colorectal cancer samples

open access: yesMolecular Oncology, Volume 19, Issue 5, Page 1332-1346, May 2025.
Consensus molecular subtypes (CMS1‐4) have been identified to study colorectal cancer heterogeneity and serve as potential biomarkers. In this study, we developed and evaluated NanoCMSer, a NanoString‐based classifier using 55 genes, optimized for FF and FFPE to facilitate the clinical evaluation of CMS subtyping.
Arezo Torang   +10 more
wiley   +1 more source

Better Strategyproof Mechanisms without Payments or Prior --- An Analytic Approach [PDF]

open access: yesarXiv, 2016
We revisit the problem of designing strategyproof mechanisms for allocating divisible items among two agents who have linear utilities, where payments are disallowed and there is no prior information on the agents' preferences. The objective is to design strategyproof mechanisms which are competitive against the most efficient (but not strategyproof ...
arxiv  

Structural response of bead-stiffened thermoplastic shear webs [PDF]

open access: yes
The results of an experimental and analytical study of the structural response and failure characteristics of selected bead-stiffened thermoplastic shear-webs are presented.
Rouse, Marshall
core   +1 more source

Addressing persistent challenges in digital image analysis of cancer tissue: resources developed from a hackathon

open access: yesMolecular Oncology, EarlyView.
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran   +16 more
wiley   +1 more source

Multi‐omics profiling reveals key factors involved in Ewing sarcoma metastasis

open access: yesMolecular Oncology, Volume 19, Issue 4, Page 1002-1028, April 2025.
Using a mouse model that recapitulates the spread of tumor cells within the body, we have profiled paired tumors and metastasis samples using a multiomics approach combining different layers of biological information. We identified key genes that drive metastasis in Ewing sarcoma.
Mariona Chicón‐Bosch   +11 more
wiley   +1 more source

Structure behind Mechanics II: Deduction [PDF]

open access: yesarXiv, 2000
This paper proves that protomechanics, previously introduced in quant-ph/9909025, deduces both quantum mechanics and classical mechanics. It does not only solve the problem of the arbitrariness on the operator ordering for the quantization procedure, but also that of the analyticity at the exact classical-limit of $\hbar =0 $.
arxiv  

Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu   +7 more
wiley   +1 more source

An Analytical Model of Sorption-Induced Static Mode Nanomechanical Sensing for Multi-Component Analytes [PDF]

open access: yesarXiv
Nanomechanical sensors and their arrays have attracted significant attention for detecting, distinguishing, and identifying target analytes, especially complex mixtures of odors. In the static mode operation, sensing signals are obtained by a concen-tration-dependent sorption-induced mechanical strain/stress.
arxiv  

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