Results 21 to 30 of about 1,564,973 (286)

Method operable design region for robust RP-HPLC analysis of pioglitazone hydrochloride and teneligliptin hydrobromide hydrate: incorporating hybrid principles of white analytical chemistry and design of experiments

Future Journal of Pharmaceutical Sciences, 2023
Background A combination of pioglitazone hydrochloride with teneligliptin hydrobromide hydrate is used to treat type-2 diabetes. Several chromatographic techniques have been described in the literature for determination of each of these medications ...
Pintu Prajapati, Bageshree Rana, Veera Shakar Pulusu, Shailesh Shah   +3 more
doaj   +1 more source

Analytical Procedure Validation and the Quality by Design Paradigm [PDF]

Journal of Biopharmaceutical Statistics, 2014
Since the adoption of the ICH Q8 document concerning the development of pharmaceutical processes following a quality by design (QbD) approach, there have been many discussions on the opportunity for analytical procedure developments to follow a similar approach.
Rozet, Eric, Lebrun, Pierre, Michiels, Jean-François, Sondag, Perceval, Scherder, Tara, Boulanger, Bruno   +5 more
openaire   +3 more sources

Development and validation of a UPLC-MS method for determination of atazanavir sulfate by the “analytical quality by design” approach

Acta Pharmaceutica, 2020
A UPLC-MS method for the estimation of atazanavir sulfate was developed using the “analytical quality by design” approach. The critical chromatographic quality attributes identified were retention time, theoretical plates and peak tailing.
Saha Chandni, Gupta N. Vishal, Chandan R. S.   +2 more
doaj   +1 more source

General Recipe for Designing Photonic Crystal Cavities [PDF]

, 2005
We describe a general recipe for designing high-quality factor (Q) photonic crystal cavities with small mode volumes. We first derive a simple expression for out-of-plane losses in terms of the k-space distribution of the cavity mode.
Englund, Dirk, Fushman, Ilya, Vuckovic, Jelena   +2 more
core   +1 more source

Eco-friendly based stability-indicating RP-HPLC technique for the determination of escitalopram and etizolam by employing QbD approach

Green Chemistry Letters and Reviews, 2022
ESC (Escitalopram) and ETZ (Etizolam) are essential anti-anxiety medications. This research suggests employing a Green Analytical Quality by Design (AQbD) based HPLC technique to determine ESC and ETZ are environmentally friendly. According to literature,
Durga Devi Perumal, Manikandan Krishnan, K.S. Lakshmi   +2 more
doaj   +1 more source

Analytical quality by design assisted RP-HPLC method for quantifying atorvastatin with green analytical chemistry perspective

Journal of Chromatography Open, 2022
Analytical Quality by design and greener solvent methods were applied to optimize the High-Performance Liquid Chromatographic method for assessing atorvastatin calcium in bulk and pharmaceutical dosage forms are highlighted in the present work.
K.S. Kokilambigai, K.S. Lakshmi
doaj   +1 more source

Isolation, identification, structural elucidation, and toxicity prediction using (Q)-SAR models of two degradants: AQbD-driven LC method to determine the Roxadustat impurities

Talanta Open, 2023
: Roxadustat (RDT) is the first orally administrated HIF-prolyl hydroxylase inhibitor drug used to treat anemia caused by chronic kidney disease. Two unknown degradants were detected in photolytic and oxidative stress conditions during the forced ...
Srinivas Nakka, Naresh Kumar Katari, Siva Krishna Muchakayala, Sreekantha Babu Jonnalagadda, Surendra Babu Manabolu Surya   +4 more
doaj   +1 more source

Searching for improvement [PDF]

, 2006
Engineering design can be thought of as a search for the best solutions to engineering problems. To perform an effective search, one must distinguish between competing designs and establish a measure of design quality, or fitness.
Atherton, MA, Bates, RA
core   +1 more source

Analysis of Compounded Pharmaceutical Products to Teach the Importance of Quality in an Applied Pharmaceutics Laboratory Course [PDF]

, 2014
Objective. To assess the effectiveness of a product-analysis laboratory exercise in teaching students the importance of quality in pharmaceutical compounding. Design.
Almoazen, Birnie, Eley, Hinkle, Kadi, McGill, Newton, Pignato, Shrewsbury, Shrewsbury   +9 more
core   +2 more sources

Quality By Design: Approach to Analytical Method Validation

Sciences of Pharmacy, 2022
A pharmaceutical industry is highly regulated by a quality policy in its management. The principles of Quality by Design (QbD) must be applied to ensure the development of pragmatic and systematic methods while managing the risks associated with analytical methods.
Mayang Dewi, Reza Pratama, Mia Arifka, Anis Chaerunisaa   +3 more
openaire   +1 more source