Results 31 to 40 of about 63,340,489 (278)

Analytical quality by design assisted RP-HPLC method for quantifying atorvastatin with green analytical chemistry perspective

Journal of Chromatography Open, 2022
Analytical Quality by design and greener solvent methods were applied to optimize the High-Performance Liquid Chromatographic method for assessing atorvastatin calcium in bulk and pharmaceutical dosage forms are highlighted in the present work.
K.S. Kokilambigai, K.S. Lakshmi
doaj   +1 more source

Analytical Quality by Design, Life Cycle Management, and Method Control [PDF]

The AAPS Journal, 2022
AbstractAnalytical methods are utilized throughout the biopharmaceutical and vaccines industries to conduct research and development, and to help control manufacturing inputs and outputs. These analytical methods should continuously provide quality data to support decisions while managing the remaining of risk and uncertainty.
Thorsten Verch, Cristiana Campa, Cyrille C. Chéry, Ruth Frenkel, Timothy Graul, Nomalie Jaya, Bassam Nakhle, Jeremy Springall, Jason Starkey, Jette Wypych, Todd Ranheim   +10 more
openaire   +2 more sources

A Kinematic Approach for 6-DOF Part Positioning [PDF]

, 2013
Lien vers la version éditeur: http://link.springer.com/chapter/10.1007%2F978-3-642-30817-8_15This article proposes a fixturing system consists of a cuboid basep-late located through a 3-2-1 configuration of locators.
ANTOINE, Jean-François, MARTIN, Patrick, Patrick Martin, BUTT, Sajid-Ullah, Sajid Ullah Butt, Jean-Francois Antoine   +5 more
core   +1 more source

Isolation, identification, structural elucidation, and toxicity prediction using (Q)-SAR models of two degradants: AQbD-driven LC method to determine the Roxadustat impurities

Talanta Open, 2023
: Roxadustat (RDT) is the first orally administrated HIF-prolyl hydroxylase inhibitor drug used to treat anemia caused by chronic kidney disease. Two unknown degradants were detected in photolytic and oxidative stress conditions during the forced ...
Srinivas Nakka, Naresh Kumar Katari, Siva Krishna Muchakayala, Sreekantha Babu Jonnalagadda, Surendra Babu Manabolu Surya   +4 more
doaj   +1 more source

Exploring the design applications of key emerging materials from natural sciences through a design ideation workshop [PDF]

, 2023
10th Congress of the International Association of Societies of Design Research (IASDR 2023) 9-13 October 2023, Milan, Italy202405 bcchVersion of ...
Wang, X, Tufail, M, Leung, Sai Yin, Park, Hyunyim, Tian, A, Uzma, S, Kim, KM, Kim, KwanMyung, Wang, Xinyi, Tufail, Muhammad, Li, X, Tian, Aichu, Leung, SY, Park, H, Li, Xinye, Uzma, Sahr   +15 more
core   +1 more source

Working within the Design Space: Do Our Static Process Characterization Methods Suffice?

Pharmaceutics, 2020
The Process Analytical Technology initiative and Quality by Design paradigm have led to changes in the guidelines and views of how to develop drug manufacturing processes.
Moritz von Stosch, René Schenkendorf, Geoffroy Geldhof, Christos Varsakelis, Marco Mariti, Sandrine Dessoy, Annick Vandercammen, Alexander Pysik, Matthew Sanders   +8 more
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Ovarian Sex Cord Stromal Tumors in Children and Adolescents—The European Standard Clinical Practice Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider, Kris‐Ann Schultz, Nora Schnitzler, Michael Abele, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Ines B. Brecht, Maja Cesen, Andrea Ferrari, Michaela Kuhlen, Malgorzata A. Krawczyk, Ricardo Lopez‐Almaraz, Yves Reguerre, Calogero Virgone, Daniel Orbach   +15 more
wiley   +1 more source

Global Regulatory Perspectives on Quality by Design in Pharma Manufacturing

, 2019
The legislations have almost frozen the processes used in pharmaceutical manufacturing overtime. Even after the receipt of drugs’ permits/certificates, even a small change in the method of manufacturing of medicines requires examination and approval of ...
Aksu, Buket, Gizem Yeğen, Buket Aksu, Yeğen, Yegen Gizem   +3 more
core   +1 more source

AQbD-novel strategy for analytical methods

Future Journal of Pharmaceutical Sciences
Background Analytical Quality by Design (AQbD) has emerged as a pivotal paradigm in the realm of analytical chemistry, revolutionizing the approach to method development and validation. This innovative strategy integrates principles of Quality by Design (
Amruta Bairagi, Rutuja Kothrukar, Hemant Chikhale, Sreya Kosanam, Laxmikant Borse   +4 more
doaj   +1 more source