Results 61 to 70 of about 1,590,893 (188)

Definições e escopo dos elementos-chave do Analytical Quality by Design (AQbD) para o desenvolvimento de métodos na indústria farmacêutica

Vigilância Sanitária em Debate: Sociedade, Ciência & Tecnologia, 2023
Introdução: O setor farmacêutico está em constante evolução e é altamente regulado com normas para garantir eficácia, segurança e qualidade dos medicamentos.
Rosemberg Bernardez Moure, Flávia Furtado de Mendonça de Sousa, Diogo Dibo do Nascimento, Jorge Lima de Magalhães, Camila Areias de Oliveira, Livia Deris Prado   +5 more
doaj   +1 more source

Assessment of computational approaches in the prediction of spectrogram and chromatogram behaviours of analytes in pharmaceutical analysis: assessment review

Future Journal of Pharmaceutical Sciences, 2023
Background Today, artificial intelligence-based computational approach is facilitating multitasking and interdisciplinary analytical research. For example, the data gathered during an analytical research project such as spectral and chromatographic data ...
M. Malarvannan, K. Vinod Kumar, Y. Padmanabha Reddy, Pallaprolu Nikhil, Dande Aishwarya, V. Ravichandiran, P. Ramalingam   +6 more
doaj   +1 more source

AQbD-enhanced green RP-UPLC-PDA methodology for quantification and forced degradation studies for omeprazole, amoxicillin, and rifabutin

BMC Chemistry
The ternary combination like omeprazole (OMP), amoxicillin (AMX), and rifabutin (RFB) was approved by the FDA in November 2019 for combating Helicobacter pylori infections and ulcers caused by this infection. This study aims to develop and authenticate a
S. P. Ashnah Baffinsha, Vijayageetha Ragupathi, Hemanth Kumar Chanduluru   +2 more
doaj   +1 more source

Quality by design-assisted green uv-spectrophotometric method development and validation for the quantitative estimation of letrozole

Drug Analytical Research
Letrozole, a potent aromatase inhibitor, is commonly used in treating hormone-responsive breast cancer. With the rising incidence of breast cancer and increased demand for anticancer agents, this study aims to develop a green, cost-effective, and ...
Shahrikh S. Pakali, Mahesh palled, Shailendra S. Suryawanshi   +2 more
doaj   +1 more source

Design of Experiments (DoE) applied to Pharmaceutical and Analytical Quality by Design (QbD)

Brazilian Journal of Pharmaceutical Sciences, 2018
According to Quality by Design (QbD) concept, quality should be built into product/method during pharmaceutical/analytical development. Usually, there are many input factors that may affect quality of product and methods. Recently, Design of Experiments (
Isa Martins Fukuda, Camila Francini Fidelis Pinto, Camila dos Santos Moreira, Alessandro Morais Saviano, Felipe Rebello Lourenço   +4 more
doaj   +1 more source

A design procedure for an acoustic mirror providing dual reflection of longitudinal and shear waves in Solidly Mounted BAW Resonators (SMRs) [PDF]

, 2009
The quality factor of the traditional Solidly Mounted Resonator (SMR) is limited by substrate losses, as the traditionally employed acoustic mirror reflects longitudinal waves but not shear waves.
Hueting, R.J.E., Jansman, A.B.M., Jose, S.   +2 more
core   +4 more sources

QbD assisted green and white analytical UPLC method quantification of pharmacopeia impurities of Pravastatin in bulk drug and pharmaceutical formulations

Journal of Applied Pharmaceutical Research
Background: A QbD-assisted green and white UPLC method was optimized for the simultaneous quantification of pravastatin and its EP impurities B, C, and D.
N. Usha Rani, P. T. S. R. K. Prasad Rao, K. Ramanjaneyulu   +2 more
doaj   +1 more source

Generation of electrical energy using lead zirconate titanate (PZT-5A) piezoelectric material: Analytical, numerical and experimental verifications [PDF]

, 2016
Energy harvesting is the process of attaining energy from the external sources and transforming it into usable electrical energy. An analytical model of piezoelectric energy harvester has been developed to determine the output voltage across an ...
Ahmad, Nasir, Anjum, Zeeshan, Butt, Zubair, Elahi, Hassan, Pasha, Riffat Asim, Qayyum, Faisal   +5 more
core   +1 more source

Eco-conscious AQbD-guided stability-indicating RP-UPLC method for analysing Tovorafenib in bulk and dosage forms

Scientific Reports
Tovorafenib is a type II RAF inhibitor recently approved by the FDA for relapsed or refractory paediatric low-grade glioma in children aged 6 months and older with BRAF fusions or V600E mutations, owing to its strong central nervous system penetration ...
Vanga Mohan Goud, Sarad Pawar Naik Bukke, Praveen Kumar Kusuma, Satla Shobha Rani, M. Sunitha Reddy, Chandrashekar Thalluri, Bayapa Reddy Narapureddy   +6 more
doaj   +1 more source

Effects of variable resistance on smart structures of cubic reconnaissance satellites in various thermal and frequency shocking conditions [PDF]

, 2017
Piezoelectric materials are widely used as smart structures in cubic reconnaissance satellites because of their sensing, actuating, and energy-harvesting abilities.
Butt, Zubair, Elahi, Hassan, Eugeni, Marco, Gaudenzi, Paolo, Israr, Asif   +4 more
core   +1 more source