Results 101 to 110 of about 2,122,180 (273)
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Progress toward a cosmic dust collection facility on space station [PDF]
, 1988 Scientific and programmatic progress toward the development of a cosmic dust collection facility (CDCF) for the proposed space station is documented. Topics addressed include: trajectory sensor concepts; trajectory accuracy and orbital evolution; CDCF ...
Carey, William C., Mackinnon, Ian D. R.
core +1 more source
Process Analytical Techniques Based on In-Line Vibrational Spectroscopy and their Industrial Applications [PDF]
Kemija u Industriji, 2013 Process analytical techniques (PAT) involve the monitoring and control of physical and chemical processes as well as the identification of important process parameters in order to obtain the products with desired properties.
Jednačak, T., Novak, P.
doaj
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Analysis of free analyte fractions by rapid affinity chromatography [PDF]
, 2004 The invention is generally directed toward an analytical method to determine the concentration of the free analyte fraction in a sample. More particularly, the method encompasses applying a sample comprising a free and bound analyte fraction to an ...
Clarke, William A., Hage, David S.
core +1 more source
Impact of Microplastics on Human Health: A Comprehensive Review
Journal of Preventive, Diagnostic and Treatment Strategies in MedicineThis comprehensive review explores microplastic (MP) contamination in food and Incorporating nanotechnology into food packaging. It covers origins, pathways, health consequences, and analytical challenges. Microplastics (MPs), which are generation due to
R. Prathipa +3 more
doaj +1 more source
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Analytical and experimental investigations of low level acceleration measurement techniques [PDF]
Construction techniques for accelerometer with low level threshold ...
Chapman, P. K. +2 more
core +1 more source
A Primer on Spreadsheet Analytics [PDF]
, 2008 This paper provides guidance to an analyst who wants to extract insight from a spreadsheet model. It discusses the terminology of spreadsheet analytics, how to prepare a spreadsheet model for analysis, and a hierarchy of analytical techniques.
Grossman, Thomas A.
core +2 more sources