Results 101 to 110 of about 64,042 (297)

A Non‐Antigenic Randomized Polyethylene Glycol/Poly(2‐Phenyl‐2‐Oxazine)‐Based Drug Delivery Platform

open access: yesMacromolecular Rapid Communications, EarlyView.
Randomized PEG (rPEG), a conceptually new PEG alternative, is combined with poly(2‐phenyl‐2‐oxazine) (PPheOzi) to establish an rPEG‐b‐PPheOzi‐b‐rPEG micellar drug delivery platform. The PPheOzi block enables high drug loadings, while competitive ELISA reveals a drastic reduction in anti‐PEG antibody affinity of rPEG in comparison to PEG.
Julian Schmidt   +6 more
wiley   +1 more source

Fractionated vaccination with mRNA COVID‐19 vaccine is safe for patients with polyethylene glycol allergy

open access: yesClinical and Translational Allergy, 2023
Charlotte G. Mortz   +6 more
doaj   +1 more source

How to manage anaphylaxis in primary care

open access: yesClinical and Translational Allergy, 2017
Anaphylaxis is defined as a severe life-threatening generalized or systemic hypersensitivity reaction characterized by rapidly developing airway and/or circulation problems.
Alberto Alvarez-Perea   +2 more
doaj   +1 more source

Real‐World Safety and Effectiveness of Glatiramer Acetate in Patients With Multiple Sclerosis: Final Results of Post‐Marketing Surveillance in Japan

open access: yesNeurology and Clinical Neuroscience, EarlyView.
ABSTRACT Background Glatiramer acetate is an injectable disease‐modifying therapy indicated for multiple sclerosis (MS). Aim To evaluate the real‐world safety and effectiveness of glatiramer acetate for MS in Japan. Methods A prospective, multicenter, observational, all‐case post‐marketing survey was conducted in Japan between November 2015 and March ...
Masaaki Niino   +3 more
wiley   +1 more source

Missed Registration of Disease Codes for Pediatric Anaphylaxis at the Emergency Department

open access: yesEmergency Medicine International, 2019
Background. It is important to register anaphylaxis codes correctly to study the exact prevalence of anaphylaxis. The purpose of this study was to analyze the clinical characteristics and disease codes of inaccurately registered groups in pediatric ...
Byungho Choi, Sun Hyu Kim, Hyeji Lee
doaj   +1 more source

Treatment of Anaphylaxis in Adults: A Questionnaire Survey

open access: yes, 2009
Objective: To identify the medications that medical students, interns and casualty medical officers are likely to prescribe when treating an adult patient with anaphylaxis, and to ascertain the dose and route of administration of adrenaline they would ...
Adiga, Shalini   +5 more
core  

Plasma Lidocaine Concentrations During Intravenous Lidocaine Infusion Therapy in the Pediatric Population—A Scoping Review

open access: yesPediatric Anesthesia, EarlyView.
ABSTRACT Background Intravenous lidocaine therapy (IVLT) is often used in perioperative multimodal analgesia due to its analgesic, anti‐hyperalgesic, and anti‐inflammatory effects. In adults, IVLT doses of 1–2 mg/kg/h produce plasma concentrations of 1–2 μg/mL, within the presumed therapeutic range of 1–5 μg/mL.
McKenna Postles   +3 more
wiley   +1 more source

Risk factors/cofactors for heightened anaphylaxis severity in Japanese adults: A 10-year single-center retrospective cohort study

open access: yesWorld Allergy Organization Journal
Background: Anaphylaxis is a severe and life-threatening allergic reaction. Although the risk factors/cofactors for anaphylaxis vary between countries and regions, limited information is available on these factors within the Japanese context.
Makoto Nojo   +5 more
doaj   +1 more source

Pediatric anaphylaxis and hyper IgE syndrome

open access: yes, 2017
Amrita Dosanjh Department of Pediatrics, Rady Childrens Hospital, San Diego, CA, USA Abstract: Patients with autosomal-dominant (AD) hyper immunoglobulin E (IgE) syndrome (HIES) or Job syndrome develop frequent dermatologic and pulmonary infections.
Dosanjh A
core  

Clinical characteristics of immediate allergic adverse reactions to intravenous amoxicillin‒clavulanic acid in conscious dogs

open access: yesVeterinary Record, EarlyView.
Abstract Background Amoxicillin‒clavulanic acid (AMC) is one of the most frequently used antibiotics in small animal practice, and reports on adverse reactions are scarce. The aim of this study was to describe the clinical characteristics of immediate allergic adverse reactions to intravenous (IV) AMC in conscious dogs. Methods The medical records of a
Leonel Frutuoso, Anna Threlfall
wiley   +1 more source

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