Results 181 to 190 of about 102,570 (330)

2015 update of the evidence base: World Allergy Organization anaphylaxis guidelines

World Allergy Organization Journal, 2015
The World Allergy Organization (WAO) Guidelines for the assessment and management of anaphylaxis provide a unique global perspective on this increasingly common, potentially life-threatening disease.
F. Estelle R. Simons, Motohiro Ebisawa, Mario Sanchez-Borges, Bernard Y. Thong, Margitta Worm, Luciana Kase Tanno, Richard F. Lockey, Yehia M. El-Gamal, Simon GA Brown, Hae-Sim Park, Aziz Sheikh   +10 more
doaj  

Six Injections of Modified Adjuvanted PQ Grass Is Effective and Well‐Tolerated in a Pivotal Phase III Trial

Allergy, EarlyView.
A pivotal Phase III DBPC adaptive trial was conducted with PQ Grass 27600 SU. The primary endpoint EAACI‐CSMS0–6 demonstrated a highly significant, clinically meaningful improvement for PQ Grass of −0.27 points (95% CI: −0.42 to −0.12), corresponding to a relative difference of −20.3% (p = 0.0005) over placebo. Highly consistent secondary endpoints and
Stefan Zielen, Jonathan A. Bernstein, Gunter J. Sturm, Marek Jutel, Oliver Pfaar, the RESONATE Investigator Group, R. Gattringer, K. Gangl, J. Potesil, T. Sykora, M. Mattauchova, P. Panzner, M. Kasl, Z. Chovancova, T. Hofstetr, J. Poloniova, A. Zlamal, J. Haas, F. Heimlich, C. Korte, S. Ballenberger, J. Grosskopf, P. Heymer, C. Bergmann, M. Froer, G. Hoheisel, U. Thieme, C. Grigat, U. Schaefer, P. El Naib, A. Schwinn, S. Runge, M. Worm, S. Pauser, M. Jandl, J.‐C. Bohn, C. von Engelhardt, A. Schaefer, J. Rieker‐Schwienbacher, M. Cuevas, S. Lassmann, Y. Yarin, T. Nyeky, I. Szanyi, V. Urban, J. Nemes, P. Borowy, Z. Siergiejko, E. Janusik, B. Tluczykont, D. Madra‐Rogacka, S. Ptaczek, I. Wojciechowska, J. Orlicz‐Widawska, M. Żurowska‐Gębala, T. Hofman, S. Tokarski, M. Bederska, A. Latos, K. Kowal, E. Markut‐Miotla, E. Pisarczyk‐Bogacka, P. Kuna, B. Majorek‐Olechowska, A. Chmielewska, B. Kucinska, C. Chwala, P. Parikh, J. Sublett, J. Weiss, J. Leflein, P. Shapero, D. McNeil, K. O’Brien, E. Sher, G. Steven, L. Ford, A. Darter, L. Clore, D. Elkayam, G. Myers, J. Matz, M. Vanderwalker, S. Smiley, J. DeAngelo, A. Montanaro, J. Delgado, W. Greisner, C. Thornblade, M. Moss, Mohamed H. Shamji, Ralph Mösges, Markus Berger, Uwe E. Berger, Lawrence DuBuske, Janice A. Layhadi, Ludger Klimek, Markus Ollert, Murray A. Skinner, Matthias F. Kramer, Pieter‐Jan de Kam   +100 more
wiley   +1 more source

PRIMROSE DERMATITIS AND ITS RELATION TO ANAPHYLAXIS [PDF]

, 1917
Charles A. Simpson
openalex   +1 more source

Oral Immunotherapy in Peanut‐Allergic Adults Using Real‐World Materials

Allergy, EarlyView.
In 21 adults initiated on peanut oral immunotherapy (OIT), 67% tolerated at least 1000 mg on exit DBPCFC. Decreases in SPT size and increases in peanut‐ and Ara h 2‐specific IgG occurred in OIT participants but not in mechanistic controls (n = 9). Improvements were seen in FAQLQ‐AF and food neophobia scores.
Hannah Hunter, Kok Loong Ue, Victoria Cornelius, Ching Ching Yung, Iason Thomas, Olympia Tsilochristou, Janice Layhadi, Leonard Q. C. Siew, Carina Venter, Mohamed H. Shamji, Stephen J. Till   +10 more
wiley   +1 more source

Anaphylaxis in the Mouse Produced with Crystalline Bovine Albumin [PDF]

, 1953
Morris Solotorovsky, Seymour Winsten
openalex   +1 more source

Efficacy and Safety of Biologics for Chronic Rhinosinusitis With Nasal Polyps: A Meta‐Analysis of Real‐World Evidence

Allergy, EarlyView.
ABSTRACT Dupilumab, omalizumab, mepolizumab, and benralizumab have demonstrated good efficacy and safety in the treatment of severe uncontrolled chronic rhinosinusitis with nasal polyps (CRSwNP) in phase 3 randomised controlled trials (RCTs). With recent regulatory approvals, there has been a surge in real‐world studies (RWSs).
Shiru Cai, Shenglong Xu, Yan Zhao, Luo Zhang   +3 more
wiley   +1 more source

THE RELATIONSHIP OF CHRONIC PROTEIN INTOXICATION IN ANIMALS TO ANAPHYLAXIS [PDF]

, 1915
WARFIELD T. LONGCOPE
openalex   +1 more source

Current use of push‐dose epinephrine: Survey and interview results from academic clinicians in emergency medicine

Academic Emergency Medicine, EarlyView.
Andrew K. Posen, Shaveta Khosla, Terry Vanden Hoek, Renee M. Petzel Gimbar   +3 more
wiley   +1 more source

Dual Inhibition of Mast Cells and Thymic Stromal Lymphopoietin Using a Novel Bispecific Antibody, CDX‐622

Allergy, EarlyView.
SCF and TSLP expression are known to drive unique immune responses leading to the onset of allergic and inflammatory diseases. Here, we describe the characterization of a novel bsAb, CDX‐622, that targets SCF and TSLP. CDX‐622 inhibits MC functions through SCF starvation and Type 2 inflammatory responses via TSLP inhibition.
Michael B. Murphy, Laura Vitale, Thomas O'Neill, Deena M. Maurer, Linda Malenchek, Andrea Crocker, Colleen Patterson, Laura Mills‐Chen, Virginia Saley, Nicole M. Antczak, James M. Boyer, Kelly M. McManus, Noe Rico Montanari, Russell A. Hammond, Joel Goldstein, Lawrence J. Thomas, Tibor Keler, Diego Alvarado   +17 more
wiley   +1 more source

Management of iron‐deficiency anemia following acute gastrointestinal hemorrhage: A narrative analysis and review

Journal of Gastroenterology and Hepatology, Volume 38, Issue 1, Page 23-33, January 2023., 2023
Abstract Many patients experiencing acute gastrointestinal bleeding (GIB) require iron supplementation to treat subsequent iron deficiency (ID) or iron‐deficiency anemia (IDA). Guidelines regarding management of these patients are lacking. We aimed to identify areas of unmet need in patients with ID/IDA following acute GIB in terms of patient ...
Angel Lanas, Jane M Andrews, James Lau, Murat Toruner, Susan E Bromley, Ian M Gralnek   +5 more
wiley   +1 more source