Results 71 to 80 of about 65,900 (283)

Overview of Diagnostic Ultrasound Safety

open access: yesJournal of Ultrasound in Medicine, EarlyView.
Ultrasound is widely regarded as a safe imaging modality; however, emerging ultrasound‐based techniques—such as shear wave elastography and contrast‐enhanced ultrasound—operate with varying acoustic output parameters that may approach or exceed traditional diagnostic limits. As these technologies are increasingly integrated into human research studies,
Saubhagya Srivastava   +5 more
wiley   +1 more source

Efficacy of Lebrikizumab in Patients With Severe Atopic Dermatitis Who Would be Eligible for Treatment Based on the South Korean Reimbursement Criteria

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Background Lebrikizumab is approved to treat patients with moderate‐to‐severe atopic dermatitis (AD). Objectives This study evaluated the 16‐week efficacy outcomes of lebrikizumab in adults and adolescents with severe AD in ADvocate trials who would be eligible for treatment based on South Korean reimbursement‐like criteria. Methods This was a
Chong Hyun Won   +11 more
wiley   +1 more source

Severe and refractory anaphylaxis in pediatric intensive care unit [PDF]

open access: hybrid, 2023
Guillaume Pouessel   +6 more
openalex   +1 more source

Polyglycerol‐Based Lipids: A Next‐Generation Alternative to PEG in Lipid Nanoparticles for Advanced Drug Delivery Systems

open access: yesMacromolecular Rapid Communications, EarlyView.
Linear polyglycerol is proposed as a PEG‐alternative in mRNA‐loaded lipid nanoparticles to limit activation of anti‐PEG antibodies and reduce immunogenicity. Resulting nanoparticles may provide similar gene delivery capabilities, while preventing binding of anti‐PEG antibodies compared to PEGylated counterparts.
Yara Ensminger   +8 more
wiley   +1 more source

Anaphylaxis triggers in a large tertiary care hospital in Qatar: a retrospective study

open access: yesWorld Allergy Organization Journal, 2018
Background Anaphylaxis is a serious allergic disease that may lead to death if not immediately recognized and treated. Triggers of anaphylaxis including food, drugs, and insect stings can vary widely.
Taghreed Abunada   +7 more
doaj   +1 more source

Thiopentone anaphylaxis [PDF]

open access: yesAnaesthesia, 1979
A fit young mother had a severe anaphylactic response to intravenous injection of sodium thiopentone, having been sensitised nearly 20 years previously.
openaire   +2 more sources

A Non‐Antigenic Randomized Polyethylene Glycol/Poly(2‐Phenyl‐2‐Oxazine)‐Based Drug Delivery Platform

open access: yesMacromolecular Rapid Communications, EarlyView.
Randomized PEG (rPEG), a conceptually new PEG alternative, is combined with poly(2‐phenyl‐2‐oxazine) (PPheOzi) to establish an rPEG‐b‐PPheOzi‐b‐rPEG micellar drug delivery platform. The PPheOzi block enables high drug loadings, while competitive ELISA reveals a drastic reduction in anti‐PEG antibody affinity of rPEG in comparison to PEG.
Julian Schmidt   +6 more
wiley   +1 more source

Poly(sarcosine) Lipid Synthesis From CO2‐Based Sarcosine‐N‐Carboxyanhydride

open access: yesMacromolecular Rapid Communications, EarlyView.
In this work, we optimize and scale‐up a CO2‐based synthesis of sarcosine‐N‐carboxyanhydride (Sar‐NCA) to the gram scale. The low toxicity and simplicity of the approach make it an attractive alternative to current toxic phosgene‐based approaches. The CO2‐based Sar‐NCA has sufficient purity for controlled polymerization.
Florian T. Kaps   +7 more
wiley   +1 more source

Multi-phasic life-threatening anaphylaxis refractory to epinephrine managed by extracorporeal membrane oxygenation (ECMO): A case report

open access: gold, 2022
Juergen Grafeneder   +10 more
openalex   +1 more source

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