Results 31 to 40 of about 4,937 (255)
Scientific Reports, 2023 Distant intercellular communication in gliomas is based on the expansion of tumor microtubuli, where actin forms cytoskeleton and GAP-43 mediates the axonal conus growth.
Aleksandrs Krigers +7 more
doaj +1 more source
Pediatric Hematology Oncology Journal, 2021 Aim: We aimed to review our experience of managing Wilms tumor in our center over a period of fifteen years with regards to disease characteristics, outcome and see how well we are doing as compared to rest of the world. Methods: All children admitted at
Naveed Ahmad +3 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Introduction Nephrogenic rests (NRs) and nephroblastomatosis (NBM) are precursor lesions for development of Wilms tumor (WT). Their association with the risk of relapse has not been properly assessed, partly due to misunderstanding of their diagnostic criteria and terminology.
Gordan M. Vujanić +5 more
wiley +1 more source
Ukrainian Neurosurgical Journal, 2009 Structural changes of brain gliomas of low-grade anaplasia exposed with a help of magnetic resonance imaging (MRI) and verified by stereotactic biopsy at 20 patients during their treatment (courses of radio- and chemotherapy) were studied.
O. Yu. Chuvashova +4 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Embryonal tumors comprise the majority of malignant central nervous system (CNS) neoplasms diagnosed in children under 3 years of age. Compared with their counterparts in older children, these tumors exhibit distinct molecular biology and a more aggressive clinical phenotype, while their management is complicated by the heightened ...
Sudarshawn Damodharan +3 more
wiley +1 more source
Hansemann’s anaplastic theory of cancer after 135 years
Frontiers in Epigenetics and EpigenomicsSummary: The term “anaplasia” was coined in 1890 to describe chromosomal changes common to primordial cancer cells, but ever since the mechanisms whereby a cell becomes anaplastic has been the subject of much speculation.
Steven Henikoff +2 more
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Ukrainian Neurosurgical Journal, 2020 The patients with glial tumors of varying degrees of anaplasia represent an imbalance in the composition of different subpopulations of immune cells, which leads to both specific immunosuppression and stimulation of the tumor process.
Mykola I. Lisianyi +3 more
doaj +1 more source
Proteomic studies of Anaplasia in Wilms Tumor [PDF]
Proteomics Insights, 2011 Wilms tumor is the most common malignant tumor in the pediatric kidney. Anaplasia, focal or diffuse as defined by histological criteria, is the most important parameter to guide the clinical treatment plan. We sought to identify and characterize potential useful biomarkers associated with anaplasia and provide insight into the peculiar molecular ...
Rong Fan +4 more
openaire +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source