Results 41 to 50 of about 125,680 (260)

A Nicotinamide Phosphoribosyltransferase Inhibitor, FK866, Suppresses the Growth of Anaplastic Meningiomas and Inhibits Immune Checkpoint Expression by Regulating STAT1

open access: yesFrontiers in Oncology, 2022
Anaplastic meningioma is classified as a World Health Organization (WHO) grade III tumor and shows a strong tendency to recur. Although the incidence of anaplastic meningioma is low, the high rate of recurrence and death still makes treatment a challenge.
Yuxuan Deng   +11 more
doaj   +1 more source

Morphological analysis of CDC2 and glycogen synthase kinase 3β phosphorylation as markers of g2 → m transition in glioma. [PDF]

open access: yes, 2011
G2 → M transition is a strategic target for glioma chemotherapy. Key players in G2 → M transition include CDC2 and glycogen synthase kinase 3β (GSK3β), which are highly regulated by posttranslational phosphorylation.
Otero, José Javier, Tihan, Tarik
core   +3 more sources

The role of surgery for anaplastic thyroid carcinoma in the era of targeted therapeutics: A scoping review

open access: yesLaryngoscope Investigative Otolaryngology, 2023
Background Questions exist regarding patient selection for surgery in anaplastic thyroid carcinoma (ATC), particularly with the advent of neoadjuvant‐targeted therapeutics.
Eoin F. Cleere   +9 more
doaj   +1 more source

Validation of vessel size imaging (VSI) in high-grade human gliomas using magnetic resonance imaging, image-guided biopsies, and quantitative immunohistochemistry. [PDF]

open access: yes, 2019
To evaluate the association between a vessel size index (VSIMRI) derived from dynamic susceptibility contrast (DSC) perfusion imaging using a custom spin-and-gradient echo echoplanar imaging (SAGE-EPI) sequence and quantitative estimates of vessel ...
Chakhoyan, Ararat   +13 more
core   +2 more sources

Resistance-promoting effects of ependymoma treatment revealed through genomic analysis of multiple recurrences in a single patient [PDF]

open access: yes, 2018
As in other brain tumors, multiple recurrences after complete resection and irradiation of supratentorial ependymoma are common and frequently result in patient death.
Dahiya, Sonika   +7 more
core   +3 more sources

A rare, pediatric, fourth-ventricular, anaplastic astrocytoma

open access: yesRadiology Case Reports, 2021
Anaplastic astrocytoma, a diffusely infiltrating, malignant, astrocytic, primary brain tumor, is most commonly observed between 30 and 50 years of age. Anaplastic astrocytomas are now classified as WHO grade III lesions, with imaging characteristics and ...
Dang Vinh Hiep, MD, PhD   +2 more
doaj   +1 more source

CTLA-4 and PD-1 ligand gene expression in epithelial thyroid cancers [PDF]

open access: yes, 2018
The dysregulation of PD-1 ligands (PD-L1 and PD-L2) and CTLA-4 ligands (CD80 and CD86) represents a tumor strategy to escape the immune surveillance. Here, the expression of PD-L1, PD-L2, CD80 and CD86 was evaluated at mRNA level in 94 patients affected ...
Antonelli, Alessandro   +15 more
core   +3 more sources

Surgical treatment for anaplastic thyroid cancer [PDF]

open access: yesArchive of Oncology, 2003
Background: Anaplastic thyroid cancer is relatively rare but extremely aggressive neoplasm. The aim of the present paper was to study the possibility of surgery for anaplastic thyroid cancer.
Živaljević Vladan R.   +5 more
doaj   +1 more source

Imaging correlates of molecular signatures in oligodendrogliomas. [PDF]

open access: yes, 2004
Molecular subsets of oligodendroglioma behave in biologically distinct ways. Their locations in the brain, rates of growth, and responses to therapy differ with their genotypes. Retrospectively, we inquired whether allelic loss of chromosomal arms 1p and
Betensky, Rebecca A   +10 more
core   +2 more sources

Survival for Children Diagnosed With Wilms Tumour (2012–2022) Registered in the UK and Ireland Improving Population Outcomes for Renal Tumours of Childhood (IMPORT) Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background The Improving Population Outcomes for Renal Tumours of childhood (IMPORT) is a prospective clinical observational study capturing detailed demographic and outcome data on children and young people diagnosed with renal tumours in the United Kingdom and the Republic of Ireland.
Naomi Ssenyonga   +56 more
wiley   +1 more source

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