Results 111 to 120 of about 11,476,807 (204)

Genomic Diversity and Clinical Variability in Pediatric Primary Cutaneous Anaplastic Large Cell Lymphoma: A Case Series

open access: yesPediatric Blood &Cancer, Volume 73, Issue 9, September 2026.
ABSTRACT Primary cutaneous anaplastic large cell lymphoma (pcALCL) is a rare pediatric CD30‐positive T‐cell lymphoproliferative disorder with an excellent prognosis, but its genomic drivers are poorly defined. We report three children with skin‐limited disease demonstrating striking molecular heterogeneity, including NPM::ALK, NUP214::FRK, and a novel ...
Shoshana Greenberger   +7 more
wiley   +1 more source

Systemic Variety of Anaplastic Large - Cell Lymphoma [PDF]

open access: yes, 2016
We present a case report of a patient with very aggressive course of anaplastic large-cell lymphoma. The patient had nonspecific complaints of easy fatigability and progressive breathlessness and had generalized lymphadenopathy.
Singh, Satender Pal   +3 more
core  

The Role of “Adult‐Onset” Cancer Predisposition Genes in Pediatric Cancer: A Comprehensive Review

open access: yesPediatric Blood &Cancer, Volume 73, Issue 9, September 2026.
ABSTRACT Current literature estimates that 10% of pediatric cancers are caused by pathogenic or likely pathogenic (P/LP) germline variants in cancer predisposition genes (CPGs). Variants in CPGs thought to increase cancer risk exclusively during adulthood are referred to as “adult‐onset” CPGs (aoCPGs).
Maria Rozo   +5 more
wiley   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

open access: yesAging and Cancer, Volume 7, Issue 3, Page 125-141, September 2026.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel   +4 more
wiley   +1 more source

Breast implant-associated anaplastic large cell lymphoma

open access: yes, 2021
Breast implant-associated anaplastic large cell lymphoma is an uncommon malignancy associated with textured breast implants, and since 2014 13 Danish cases have been identified. Early diagnosis is important to minimise morbidity.
Hölmich, Lisbeth Rosenkrantz   +2 more
core   +1 more source

Efficacy and Safety of Initial Low‐Dose, Extended‐Interval Nivolumab Monotherapy in a 91‐Year‐Old Patient With Locally Advanced NSCLC and Poor Performance Status: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT The incidence of non‐small cell lung cancer (NSCLC) increases with age, with approximately half of the cases diagnosed in individuals aged 70 and older. In numerous clinical trials, immune checkpoint inhibitors (ICIs) have demonstrated significant efficacy in treating NSCLC without driver gene mutations.
Dan Kou   +6 more
wiley   +1 more source

Anaplastic large cell lymphoma

open access: yes, 2014
Anaplastic large cell lymphoma (ALCL) is a rare lymphoid malignancy that is characterized by the expression of CD30 cell surface receptor and by a chromosomal translocation that results in aberrant constitutive activation of the anaplastic large cell ...
Zinzani P. L.   +3 more
core   +1 more source

Oral Relapsing Lymphomatoid Papulosis: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Lymphomatoid papulosis (LyP) is a CD30+ T‐cell lymphoproliferative disorder rarely involving mucosa, where it may mimic aggressive lymphomas. This case highlights its chronic relapsing course, diagnostic challenges with ALK‐negative anaplastic T‐cell lymphoma, and the importance of long‐term follow‐up despite a favorable prognosis.
A. Bitton   +7 more
wiley   +1 more source

Hodgkin Reed–Sternberg‐Like Cells in T‐Cell/Histiocyte‐Rich Large B‐Cell Lymphoma

open access: yes
eJHaem, Volume 7, Issue 5, October 2026.
Ulysses Mustaki   +3 more
wiley   +1 more source

Payload‐Based Clinical Pharmacology Review of Approved Antibody–Drug Conjugates: Commonalities and Considerations for Streamlined Development

open access: yesClinical Pharmacology &Therapeutics, Volume 120, Issue 3, Page 614-638, September 2026.
Antibody–drug conjugates (ADCs) combine the specificity of an antibody with the potency of a cytotoxic drug. Thirteen ADCs, utilizing seven unique cytotoxic payloads and targeting 11 distinct antigens, are currently approved by the US Food and Drug Administration as of June 2025, representing a rapidly growing and highly promising class of anticancer ...
Sijie Lu   +6 more
wiley   +1 more source

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