Results 51 to 60 of about 11,476,807 (204)

Achieving Reliable Diagnosis in Late Breast Implant Seromas. From Reactive to Anaplastic Large Cell Lymphoma

, 2019
Late onset of fluid collection surrounding breast implants may represent a serious issue when considering the possibility of breast implant-associated anaplastic large cell lymphoma, a newly recognized type of T-cell malignancy.
Di Napoli, Arianna
core   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

Anaplastic large cell lymphoma mimicking a psoas abscess

Journal of Pediatric Surgery Case Reports, 2020
We report a case of Anaplastic Large Cell Lymphoma mimicking a psoas abscess in a 6-year-old girl which posed significant diagnostic challenges. She presented with a vague two-month history of anaemia, fevers and back and abdominal pain.
Arushi Singh, Piyumi De Silva, Janis Chamberlain, Aniruddh Deshpande   +3 more
doaj   +1 more source

Primary cutaneous anaplastic large-cell lymphoma in a patient with Hodgkin’s disease – case report

, 2016
Introduction. Cutaneous anaplastic large cell lymphoma (C-ALCL) is one of the CD30+ lymphoproliferative disorders. Usually it has a mild course and does not require aggressive treatment. The prognosis in C-ALCL is good, with the 10-year survival rate
Dorota Kozłowska, Anna Baran, Iwona Flisiak   +2 more
core   +1 more source

Etiology of breast implant-associated anaplastic large cell lymphoma (Bia-alcl): Current directions in research

, 2020
Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is a CD30-positive, anaplastic lymphoma kinase-negative T-cell lymphoma. Where implant history is known, all confirmed cases to date have occurred in patients with exposure to textured ...
Magnusson, MR, Kadin, ME, Miranda, RN, Deva, AK, Turner, SD, Adams, WP, Prince, HM, Inghirami, GG   +7 more
core   +1 more source

Aberrant expression of and cell death induction by engagement of the MHC-II chaperone CD74 in anaplastic large cell lymphoma (ALCL) [PDF]

, 2021
In 50-60% of cases, systemic anaplastic large cell lymphoma (ALCL) is characterized by the t(2;5)(p23;q35) or one of its variants, considered to be causative for anaplastic lymphoma kinase (ALK)-positive (ALK(+)) ALCL.
Stein, Harald, Wurster, K.D., Michael Hummel, Arturo Molina, Janz, M., Karl Köchert, Anagnostopoulos, I., Mathas, S., Kathrin Wurster, Selina Glaser, Harald Stein, Stephan Mathas, Gillissen, B., Glaser, Selina, Glaser, S., Anagnostopoulos, Ioannis, Siebert, Reiner, Hummel, Michael, Bernd Gillissen, Diepstra, A., Köchert, K., Schleussner, Nikolai, Lamprecht, B., Reiner Siebert, Wurster, Kathrin D, Diepstra, Arjan, Diepstra, Arjan; id_orcid, Merkel, Olaf, Nikolai Schleussner, Stephan Kreher, Siebert, R., Korinna Jöhrens, Schleussner, N., Cheng, Alfred Sze-Lok, Costanza, Mariantonia, Molina, Arturo, Björn Lamprecht, Jöhrens, Korinna, Kreher, S., Ioannis Anagnostopoulos, Kenner, L., Wurster, Kathrin D., Hummel, M., Stein, H., Jöhrens, K., Gillissen, Bernd, Mathas, Stephan, Martin Janz, Mariantonia Costanza, Molina, A., Lukas Kenner, Kreher, Stephan, Köchert, Karl, Arjan Diepstra, Janz, Martin, Olaf Merkel, Costanza, M., Lamprecht, Björn, Merkel, O., Kenner, Lukas   +59 more
core   +2 more sources

From anthelmintic to neuro‐oncology: A systematic review of mebendazole repurposing for brain tumour therapy

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Mebendazole (MBZ), a benzimidazole anthelmintic with established clinical use, has emerged as a repurposing candidate for primary brain tumours due to its multimodal anticancer actions and central nervous system penetrance. This systematic review synthesizes preclinical and clinical evidence evaluating MBZ's efficacy, mechanisms of action ...
Ciara B. Blum, Milli McMenamin, Tessa Khoo, John M. Edwin, Prathibha Jose, Liam A. O’Callaghan   +5 more
wiley   +1 more source

Efficacy and Safety of Durvalumab and Tremelimumab in Metastatic Non‐Small Cell Lung Cancer: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials

Chronic Diseases and Translational Medicine, EarlyView.
PRISMA 2020 flow diagram of included studies. ABSTRACT Purpose Immune checkpoint inhibitors have transformed treatment strategies for metastatic non‐small cell lung cancer (mNSCLC). This study aimed to assess the efficacy and safety of durvalumab combined with tremelimumab compared with those of standard chemotherapy, particularly in patients with low ...
Ikhwan Rinaldi, Eric Ricardo Yonatan, Tasia Esterita   +2 more
wiley   +1 more source

Utility of Fine Needle Aspiration Supernatant for Real‐Time PCR–Based Mutation Analysis in Non–Small Cell Lung Cancer

Diagnostic Cytopathology, EarlyView.
ABSTRACT Background The emergence of personalized therapy and molecular sequencing has significantly transformed the management of advanced non–small cell lung carcinoma (NSCLC). Supernatants obtained from fine needle aspiration (FNA) have been shown to be a reliable source of high‐quality nucleic acid for molecular testing.
Adeyinka Akinsanya, Riley Gorden, Madison Rector, Hamna Muhammad, Melissa Randolph, Matt Sperling, Kemin Xu, Sheila Segura, Omer Saeed, Tieying Hou   +9 more
wiley   +1 more source

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source