Results 71 to 80 of about 11,476,807 (204)

Breast implant-associated anaplastic large cell lymphoma: a review [PDF]

open access: yes, 2018
El texto completo de este trabajo no está disponible en el Repositorio Académico UPC por restricciones de la casa editorial donde ha sido publicado.Breast implant-associated anaplastic large cell lymphoma is a newly recognized provisional entity in the ...
Miranda, Roberto N.   +5 more
core   +1 more source

Nanomedicine applications in lymphoma: Advancing precision diagnostics, targeted therapeutics, and prospective developments

open access: yesVIEW, EarlyView.
Lymphoma is a group of blood cancers that can appear in lymph nodes, blood, bone marrow, spleen, liver, or the central nervous system, which makes drug delivery and disease monitoring difficult. This review summarizes how nanomedicine technologies may improve targeted treatment and imaging, while carefully separating approved or guideline‐supported ...
Mohd Ahmar Rauf   +5 more
wiley   +1 more source

Anaplastic Large Cell Lymphoma [PDF]

open access: yes, 2019
Anaplastic Large Cell Lymphoma (ALCL) describes a distinct group of T cell lymphomas characterized by cell surface expression of CD30. At least 3 entities of ALCL exist, with similar cellular morphology but varying clinical courses and pathology ...
Suzanne D. Turner
core   +2 more sources

Advances in γδ T Cells: Cutaneous Biology and Therapeutic Potential for Skin Neoplasms

open access: yesThe Journal of Dermatology, EarlyView.
ABSTRACT γδ T cells represent an increasingly important subset of T lymphocytes in the immune response to cancer and as a platform for novel immunotherapies. The aim of this review is to synthesize recent insights into the biology and advances in therapeutic applications of γδ T cells in cutaneous malignancies, especially melanoma, within a framework ...
Simo Du   +9 more
wiley   +1 more source

Breast implant-associated anaplastic large cell lymphoma in the post-mastectomy setting: Clinical and therapeutic implications

open access: yesHuman Pathology: Case Reports, 2019
We report a case of breast implant-associated anaplastic large cell lymphoma in a 70-year old woman, who 21 years previously had undergone bilateral breast augmentation with textured silicone implants.
Cristiane B. Milito   +3 more
doaj   +1 more source

ALK-positive anaplastic large cell lymphoma presenting as intradural spinal mass: First reported case and review of literature

open access: yes, 2013
Anaplastic large cell lymphoma (ALCL) is characterized by large anaplastic cells of T-cell or null-cell phenotype expressing CD30 (Ki-1 antigen). In most cases this neoplasm expresses the anaplastic lymphoma kinase (ALK), a chimeric protein resulting ...
Mariangela Novello   +11 more
core   +1 more source

A phase IIa study of the anti‐PD‐L1 antibody avelumab in relapsed/refractory PTCL: The AVAIL‐T trial

open access: yesBritish Journal of Haematology, EarlyView.
The AVAIL‐T study, the first evaluation of programmed death ligand 1 (PD‐L1) blockade in relapsed/refractory peripheral T‐cell lymphomas (PTCL), demonstrated limited single agent activity with durable responses seen in a minority. Circulating tumour DNA revealed distinct mutational dynamics and mass cytometry identified perturbed T‐cell subsets ...
Matthew J. Ahearne   +28 more
wiley   +1 more source

Anaplastic large cell lymphoma, ALK-negative [PDF]

open access: yes, 2017
Review on Anaplastic large cell lymphoma, ALK-negative, with data on clinics, and the genes ...
Feldman, Andrew L, Boddicker, Rebecca L
core   +1 more source

New Treatment Strategy and Future Research Direction for BRAF‐Mutated Cancer

open access: yesCancer Science, EarlyView.
Treatment with BRAF inhibitor plus MEK inhibitor is currently used in BRAF‐mutated various malignancies except colorectal cancer, and treatments with BRAF and/or MEK inhibitors and anti‐EGFR antibody are used in BRAF‐mutated colorectal cancer. Despite recent advances in BRAF‐targeted therapies, their efficacy is still limited.
Masanobu Takahashi   +2 more
wiley   +1 more source

Blockade of crizotinib-induced BCL2 elevation in ALK-positive anaplastic large cell lymphoma triggers autophagy associated with cell death

open access: yesHaematologica, 2019
Anaplastic lymphoma kinase (ALK)-positive anaplastic large cell lymphomas are tumors that carry translocations involving the ALK gene at the 2p23 locus, leading to the expression of ALK tyrosine kinase fusion oncoproteins.
Avedis Torossian   +9 more
doaj   +1 more source

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