Results 71 to 80 of about 47,907 (235)

Gastric cancer is the leading cause of death in Italian adult patients with common variable immunodeficiency [PDF]

, 2018
An increased prevalence of malignant lymphoma and of gastric cancer has been observed in large cohorts of patients with common variable immunodeficiency (CVID), the most frequently symptomatic primary immunodeficiency. Surveillance strategies for cancers
Agostini, Carlo, Cinetto, Francesco, Crescenzi, Ludovica, Milito, Cinzia, Pecoraro, Antonio, Pulvirenti, Federica, Quinti, Isabella, Rizzo, Francesca, Santangeli, Enrico, Spadaro, Giuseppe, Tabolli, Stefano, Valente, Michele   +11 more
core   +3 more sources

Mycosis Fungoides Is a Proliferation of Multiple Mutational Subclones

The Journal of Dermatology, EarlyView.
ABSTRACT Mycosis fungoides (MF) is a unique type of lymphoma with an excellent prognosis presenting with a wide variety of clinical and histological findings. Recent sophisticated research techniques have revealed that very slow changes in the clinical and histological pictures of one patient over time are due to intratumoral heterogeneity.
Ryoma Honda, Toshihisa Hamada, Makoto Sugaya   +2 more
wiley   +1 more source

CD30-positive peripheral T-cell lymphomas share molecular and phenotypic features

Haematologica, 2013
Peripheral T-cell lymphoma, not otherwise specified is a heterogeneous group of aggressive neoplasms with indistinct borders. By gene expression profiling we previously reported unsupervised clusters of peripheral T-cell lymphomas, not otherwise ...
Bettina Bisig, Aurélien de Reyniès, Christophe Bonnet, Pierre Sujobert, David S. Rickman, Teresa Marafioti, Georges Delsol, Laurence Lamant, Philippe Gaulard, Laurence de Leval   +9 more
doaj   +1 more source

Atezolizumab + Chemotherapy for Advanced Non‐Small Cell Lung Cancer in Japanese Clinical Practice (J‐TAIL‐2)

Cancer Science, EarlyView.
The J‐TAIL‐2 prospective, observational study evaluated atezolizumab combined with several chemotherapy regimens in patients with advanced/metastatic non‐small cell lung cancer in routine clinical practice in Japan. The real‐world efficacy and safety of each atezolizumab combination were found to be comparable to those seen in the relevant global ...
Hiroshige Yoshioka, Makoto Nishio, Kadoaki Ohashi, Atsushi Osoegawa, Eiki Kikuchi, Hideharu Kimura, Yasushi Goto, Junichi Shimizu, Eisaku Miyauchi, Ichiro Yoshino, Toshihiro Misumi, Yasutaka Watanabe, Akito Hata, Akira Kisohara, Shoichi Kuyama, Masafumi Yamaguchi, Asako Miwa, Shunichiro Iwasawa, Misa Tanaka, Akihiko Gemma   +19 more
wiley   +1 more source

ALK-negative anaplastic large-cell lymphoma [PDF]

Blood, 2016
In this issue of Blood , [Scarfo et al][1] describe a novel subset of anaplastic lymphoma kinase (ALK)-negative anaplastic large-cell lymphoma (ALCL) associated with aberrant expression of ERBB4 transcripts and potential clinical relevance.[1][2] ![Figure][3] Schematic representation ...
Philippe, Gaulard, Laurence, de Leval
openaire   +2 more sources

Breast implant-associated anaplastic large cell lymphoma in the post-mastectomy setting: Clinical and therapeutic implications

Human Pathology: Case Reports, 2019
We report a case of breast implant-associated anaplastic large cell lymphoma in a 70-year old woman, who 21 years previously had undergone bilateral breast augmentation with textured silicone implants.
Cristiane B. Milito, Francisco Beca, Yasodha Natkunam, Stephen Cook   +3 more
doaj   +1 more source

Phase 1/2 Study of Crizotinib in Children With Relapsed/Refractory ALK‐Positive Anaplastic Large Cell Lymphoma or Neuroblastoma in Japan

Cancer Science, EarlyView.
The safety and antitumor activity of crizotinib at a dose of 165 mg/m2 BID were evaluated in 16 patients with ALK‐positive ALCL in Japan. The most common grade 3 or 4 adverse event was neutropenia. The steady‐state Cmax and AUCtau of crizotinib at 165 mg/m2 BID were higher than expected. The objective response rate was 72.7% (90% CI, 43.6%–92.1%) among
Tetsuya Mori, Akiko Kada, Tomoo Osumi, Daisuke Tomizawa, Yuhki Koga, Reiji Fukano, Kengo Takeuchi, Ukihide Tateishi, Osamu Miyazaki, Ryuta Asada, Akiko M. Saito, Kei Fukuhara, Masahiro Sekimizu   +12 more
wiley   +1 more source

A comprehensive microarray-based DNA methylation study of 367 hematological neoplasms [PDF]

, 2011
Background: Alterations in the DNA methylation pattern are a hallmark of leukemias and lymphomas. However, most epigenetic studies in hematologic neoplasms (HNs) have focused either on the analysis of few candidate genes or many genes and few HN entities,
Agirre, Xabier, Alvarez, Sara, Ammerpohl, Ole, Bibikova, Marina, Brüggemann, Monika, Bug, Stefanie, Calasanz, Maria J., Cruz Cigudosa, Juan, Deckert, Martina, Dreyling, Martin, Du, Ming Q., Dyer, Martin J. S., Dürig, Jan, Fan, Jian-Bing, Gesk, Stefan, Haferlach, Claudia, Hansmann, Martin-Leo, Harder, Lana, Hartmann, Sylvia, Klapper, Wolfram, Küppers, Ralf, Martin-Subero, Jose Ignacio, Montesinos-Rongen, Manuel, Nagel, Inga, Pott, Christiane, Prosper, Felipe, Richter, Julia, Román-Gómez, José, Seifert, Marc, Siebert, Reiner, Stein, Harald, Suela, Javier, Trümper, Lorenz, Vater, Inga, Wickham-Garcia, Eliza   +34 more
core  

Extreme Hypoglycaemia in Anaplastic Large Cell Lymphoma [PDF]

, 2017
Introduction: Hypoglycaemia associated with non-islet cell tumours (NICTH) is a rare entity in patients with extra-pancreatic malignancies, mostly attributed to large mesenchymal or epithelial tumours.
Akavia, Lidor, Krauze, Ilan
core   +3 more sources

Precision Oncology for Pediatric Solid Tumors Using In‐Hospital Pediatric/AYA Malignancy‐Specific Panel Sequencing

Cancer Science, EarlyView.
Our findings indicate that a pediatric/AYA‐specific targeted panel deployed in a hospital can deliver rapid, clinically actionable molecular insights with high diagnostic and prognostic yield. This complements larger sequencing platforms by offering speed, focused content, and easier interpretation.
Masato Kojima, Sho Kurihara, Isamu Saeki, Ryo Touge, Keigo Nakashima, Shuhei Karakawa, Fumiyuki Yamasaki, Satoshi Okada, Eiso Hiyama   +8 more
wiley   +1 more source