Results 121 to 130 of about 42,587 (212)

ALK: Anaplastic lymphoma kinase

, 2013
Introduction Anaplastic lymphoma kinase, (also known as ALK, CD246 antigen, Ki 1 antigen, ALK tyrosine kinase receptor) is a member of the receptor tyrosine kinase (RTK) family. These proteins are essential for the transmission of extra-cellular signals to the interior of the cell and play essential roles in cellular activities including cell-cycle ...
openaire   +1 more source

Research Progress of ALK Activation Pattern Changes and Targeted Therapy 
in Advanced Lung Cancer

Chinese Journal of Lung Cancer
Lung cancer is the most common cancer in China and even in the world, and it is also the main cause of cancer death. Patients with anaplastic lymphoma kinase (ALK) gene alterations have the opportunity to receive molecularly targeted therapies.
Aojiao WEI, Bo JIANG, Yurong HUANG, Mengyun LIU, Jing YAN, Yuanyuan ZHAO, Wenjie HE   +6 more
doaj   +1 more source

Pitfalls in the Diagnosis of Anaplastic Large Cell Lymphoma with a Small Cell Pattern

Case Reports in Hematology, 2013
Anaplastic large cell lymphoma with a small cell pattern is a rare T-cell lymphoma. This condition is more frequently seen in younger patients and should be considered when patients present with leucocytosis and constitutional symptoms.
Rowan L. Grigoropoulos, Penny Wright, Mars B. van t'Veer, Mike A. Scott, George A. Follows   +4 more
doaj   +1 more source

ALK-driven tumors and targeted therapy: focus on crizotinib

Pharmacogenomics and Personalized Medicine, 2014
Carlos Murga-Zamalloa, Megan S Lim Department of Pathology, University of Michigan, Ann Arbor, MI, USA Abstract: Receptor tyrosine kinases have emerged as promising therapeutic targets for a diverse set of tumors.
Murga-Zamalloa C, Lim MS
doaj  

Atypical Presentation of Anaplastic Lymphoma Kinase–Positive Anaplastic Large T-Cell Lymphoma in a Young Patient With Intramuscular Nodules

Annals of Internal Medicine: Clinical Cases
Anaplastic lymphoma kinase–positive anaplastic large cell lymphoma (ALK+ ALCL) is a rare subtype of T-cell non-Hodgkin lymphoma. It commonly presents at advanced stages with B symptoms and lymphadenopathy.
Megan E. Kelley, Nicholas Joseph DeLuca, Daniel Del Castillo Rix, Jonathan H. Schatz, Rafael E. Hernandez Oquet   +4 more
doaj   +1 more source

Hubungan Kuantitatif Struktur Aktivitas Secara In Silico Senyawa 1-Benzil-3-benzoilurea dan Analognya Sebagai Antikanker Melalui Hambatan Reseptor ALK [PDF]

, 2017
Latar belakang: Reseptor ALK merupakan salah satu reseptor tirosin kinase untuk pembelahan sel, diferensiasi, dan antiapoptosis. Apabila ALK bermutasi, akan menyebabkan neuroblastoma, ALCL, IMT, NSCLC.
., Siswandono, Suhud, Farida, Wibowo, Bayu Sugio   +2 more
core  

Atypical course of Anaplastic Large Cell Lymphoma with positive anaplastic lymphoma kinase (ALK+ALCL) [PDF]

Polish Archives of Internal Medicine, 2021
Sławomir, Mrowiec, Beata, Jabłońska, Lesia, Rozłucka, Agata, Janoska-Gawrońska, Jacek, Pająk, Michał, Holecki   +5 more
openaire   +2 more sources

Fetal Lung Interstitial Tumor: A Comprehensive Case Study with an Emphasis on Next-Generation Sequencing

Journal of Chest Surgery
Fetal lung interstitial tumor (FLIT), which is characterized by immature interstitial cells resembling the fetal lung parenchyma of 20 to 24 weeks of gestation, is a rare respiratory neoplasm. This study presents the first reported FLIT in Korea.
Yoo Jin Jung, Seongyeon Jung, Jiwon Koh, Jaemoon Koh, Yoon Kyung Jeon, Sung-Hye Park, Eun Na Kim, Chang Hyun Kang   +7 more
doaj   +1 more source

Anaplastic lymphoma kinase (ALK) [PDF]

Science-Business eXchange, 2008
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Long‐term effects of crizotinib in ALK‐positive tumors (excluding NSCLC): A phase 1b open‐label study [PDF]

, 2018
et al,, Gambacorti-Passerini, Carlo, Van Tine, Brian A   +2 more
core   +1 more source