Results 11 to 20 of about 42,587 (212)
Leukemic phase of anaplastic lymphoma kinase positive, anaplastic large cell lymphoma
Indian Journal of Pathology and Microbiology, 2011 Anaplastic large cell lymphoma (ALCL) is a distinct type of CD30+ T/null-cell non-Hodgkin′s lymphoma that frequently involves nodal and extranodal sites.
Vijaya S Gadage +8 more
doaj +3 more sources
Developments in anaplastic large-cell lymphoma: targeting the anaplastic lymphoma kinase
Blood and Lymphatic Cancer: Targets and Therapy, 2014 Francesca Farina, Alessandra Stasia, Carlo Gambacorti-Passerini Department of Health Sciences, University of Milano Bicocca, Monza, Italy Abstract: Anaplastic lymphoma kinase (ALK) is a receptor tyrosine kinase protein implicated in a variety of ...
Farina F +2 more
doaj +3 more sources
ALK (anaplastic lymphoma kinase) [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011 Review on ALK (anaplastic lymphoma kinase), with data on DNA, on the protein encoded, and where the gene is implicated.
JL Huret, S Senon
openaire +4 more sources
Anaplastic Lymphoma Kinase-Negative Anaplastic Large Cell Lymphoma with Colon Involvement [PDF]
Canadian Journal of Gastroenterology and Hepatology, 2015 1Department of Gastroenterology and Hepatology; 2Department of Pathology, National Hospital Organization, Osaka National Hospital, Osaka, Japan Correspondence and reprints: Dr Yuko Sakakibara, Department of Gastroenterology and Hepatology, National Hospital Organization, Osaka National Hospital, 2-1-14 Houenzaka, Chuo-ku, Osaka city, Osaka 540-0006 ...
Yuko Sakakibara +9 more
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Anti-ALK Antibodies in Patients with ALK-Positive Malignancies Not Expressing NPM-ALK. [PDF]
, 2016 Patients with Nucleophosmin (NPM)- Anaplastic Lymphoma Kinase (ALK) fusion positive Anaplastic Large Cell Lymphoma produce autoantibodies against ALK indicative of an immune response against epitopes of the chimeric fusion protein.
Burke, Amos +13 more
core +6 more sources
Haematologica, 2018 Patients with anaplastic lymphoma kinase-positive anaplastic large cell lymphoma often present with B-symptoms or hemophagocytosis and generate an anti-tumor immune response.
Fabian Knörr +6 more
doaj +1 more source
Trop2 and its overexpression in cancers: regulation and clinical/therapeutic implications. [PDF]
, 2014 Trop2 is a transmembrane glycoprotein encoded by the Tacstd2 gene. It is an intracellular calcium signal transducer that is differentially expressed in many cancers. It signals cells for self-renewal, proliferation, invasion, and survival.
Bonavida, Benjamin, Shvartsur, Anna
core +2 more sources
Anaplastic lymphoma kinase inhibitor-associated myositis [PDF]
Neurology Neuroimmunology & Neuroinflammation, 2020 Anaplastic lymphoma kinase (ALK) inhibitors have been used in patients with non-small cell lung cancer (NSCLC) harboring EML4 - ALK fusion gene.1 Severe skeletal muscle adverse events of ALK inhibitors, such as muscle weakness, have seldom been reported.2,3 Herein, we describe a patient who showed a severe skeletal muscle deficit after the ...
Uruha, Akinori +7 more
openaire +2 more sources
Relationship of Driver Oncogenes to Long-Term Pemetrexed Response in Non--Small-Cell Lung Cancer. [PDF]
, 2015 BackgroundPemetrexed is approved in the treatment of advanced stage nonsquamous non-small-cell lung cancer (NSCLC). The length of response is variable, and we thus sought to identify which clinicopathologic characteristics are associated with long-term ...
Liang, Ying +2 more
core +1 more source
Primary nodal peripheral T-cell lymphomas: diagnosis and therapeutic considerations
Revista Brasileira de Hematologia e Hemoterapia, 2015 Nodal peripheral T-cell lymphomas are a rare group of neoplasms derived from post-thymic and activated T lymphocytes. A review of scientific articles listed in PubMed, Lilacs, and the Cochrane Library databases was performed using the term "peripheral T ...
Luis Alberto de Pádua Covas Lage +6 more
doaj +1 more source