Results 21 to 30 of about 686,182 (220)

Anaplastic Lymphoma Kinase-Negative Anaplastic Large Cell Lymphoma with Colon Involvement [PDF]

open access: yesCanadian Journal of Gastroenterology and Hepatology, 2015
1Department of Gastroenterology and Hepatology; 2Department of Pathology, National Hospital Organization, Osaka National Hospital, Osaka, Japan Correspondence and reprints: Dr Yuko Sakakibara, Department of Gastroenterology and Hepatology, National Hospital Organization, Osaka National Hospital, 2-1-14 Houenzaka, Chuo-ku, Osaka city, Osaka 540-0006 ...
Yuko Sakakibara   +9 more
doaj   +3 more sources

Anaplastic lymphoma kinase status in rhabdomyosarcomas [PDF]

open access: yesModern Pathology, 2013
Rhabdomyosarcoma is a rare soft tissue sarcoma that typically affects children, adolescents, and young adults. Despite treatment via a multidisciplinary approach, the prognosis of advance-stage rhabdomyosarcomas remains poor, and a new treatment strategy is needed.
Akihiko, Yoshida   +8 more
openaire   +2 more sources

How does conformational flexibility influence key structural features involved in activation of anaplastic lymphoma kinase? [PDF]

open access: yes, 2014
Anaplastic Lymphoma Kinase (ALK) plays a major role in developing tumor processes and therefore has emerged as a validated therapeutic target. Applying atomistic molecular dynamics simulations on the wild type enzyme and the nine most frequently ...
Lee, Christian   +4 more
core   +1 more source

Identification and characterization of peripheral T-cell lymphoma-associated SEREX antigens. [PDF]

open access: yes, 2011
Peripheral T-cell lymphomas (PTCL) are generally less common and pursue a more aggressive clinical course than B-cell lymphomas, with the T-cell phenotype itself being a poor prognostic factor in adult non-Hodgkin lymphoma (NHL).
Graham P. Collins   +34 more
core   +2 more sources

Origin and pathogenesis of nodular lymphocyte–predominant Hodgkin lymphoma as revealed by global gene expression analysis [PDF]

open access: yes, 2008
The pathogenesis of nodular lymphocyte–predominant Hodgkin lymphoma (NLPHL) and its relationship to other lymphomas are largely unknown. This is partly because of the technical challenge of analyzing its rare neoplastic lymphocytic and histiocytic (L&H ...
Tiacci, Enrico   +29 more
core   +1 more source

Primary nodal peripheral T-cell lymphomas: diagnosis and therapeutic considerations

open access: yesRevista Brasileira de Hematologia e Hemoterapia, 2015
Nodal peripheral T-cell lymphomas are a rare group of neoplasms derived from post-thymic and activated T lymphocytes. A review of scientific articles listed in PubMed, Lilacs, and the Cochrane Library databases was performed using the term "peripheral T ...
Luis Alberto de Pádua Covas Lage   +6 more
doaj   +1 more source

ALK1-Negative Anaplastic Large Cell Lymphoma of the Breast from a Nonprosthesis Cyst

open access: yesPlastic and Reconstructive Surgery, Global Open, 2014
Summary: Anaplastic large cell lymphoma of the breast is a rare malignancy associated with prosthetic breast implants. We present a case of a woman with no prior history of breast implants who developed anaplastic lymphoma kinase-1 negative anaplastic ...
Christopher Mulligan, MBBS   +5 more
doaj   +1 more source

Anaplastic lymphoma kinase negative anaplastic large cell lymphoma of hard palate as first clinical manifestation of acquired immune deficiency syndrome

open access: yesContemporary Clinical Dentistry, 2016
Anaplastic large cell lymphoma (ALCL) is an uncommon disease, accounting for
Anjali Narwal   +3 more
doaj   +1 more source

β-catenin is constitutively active and increases STAT3 expression/activation in anaplastic lymphoma kinase-positive anaplastic large cell lymphoma

open access: yesHaematologica, 2011
Background The role of β-catenin in cancer has been most studied in tumors of epithelial cell origin. The functional status and biological significance of this protein in anaplastic lymphoma kinase (ALK)-positive anaplastic large cell lymphoma is unknown.
Mona Anand, Raymond Lai, Pascal Gelebart
doaj   +1 more source

Holistic View of ALK TKI Resistance in ALK-Positive Anaplastic Large Cell Lymphoma

open access: yesFrontiers in Oncology, 2022
Anaplastic lymphoma kinase (ALK) is a receptor tyrosine kinase expressed at early stages of normal development and in various cancers including ALK-positive anaplastic large cell lymphoma (ALK+ ALCL), in which it is the main therapeutic target.
Yuan Wang   +11 more
doaj   +1 more source

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