Results 81 to 90 of about 686,182 (220)

Anaplastic large cell lymphoma presenting as a cerebellar mass

Hematology/Oncology and Stem Cell Therapy, 2014
Anaplastic large cell lymphoma (ALCL) is a T cell lymphoma occurring commonly in childhood and rarely in adults. Central nervous system involvement in ALCL is very rare and cerebellar involvement at presentation has never been described.
N Geetha, KP Sreelesh, Rekha Nair, Anitha Mathews   +3 more
doaj   +1 more source

Identification of APBB1 as a substrate for anaplastic lymphoma kinase. [PDF]

J Biochem
Abstract Anaplastic lymphoma kinase (ALK) is a well-known oncogene involved in various malignancies such as anaplastic large cell lymphoma, lung cancer and neuroblastoma. Several substrates for fused ALK have been identified and their biological functions have been described.
Suzuki Y, Tsubota S, Kadomatsu K, Sakamoto K.   +3 more
europepmc   +3 more sources

Phase II Study of Cisplatin/Gemcitabine Plus Necitumumab for Squamous NSCLC After ICI‐Platinum Therapy (WJOG14120L)

Cancer Science, EarlyView.
WJOG14120L NESSIE evaluated cisplatin, gemcitabine, and necitumumab (CGN) as second‐line therapy after ICI‐based treatment in 46 patients with advanced squamous NSCLC. ORR was 26.1%, DCR 87.0%, and median PFS 4.4 months. Although the predefined ORR threshold was not met, CGN showed modest antitumor activity with manageable toxicity.
Hiroshige Yoshioka, Keita Mori, Nobuhisa Ishikawa, Hiroaki Kanemura, Koichi Azuma, Yukihiro Toi, Hiroshi Handa, Yosuke Tamura, Hiroaki Akamatsu, Haruko Daga, Masafumi Yamaguchi, Teppei Yamaguchi, Yuki Sato, Nobuyuki Yamamoto, Kazuhiko Nakagawa, Takayasu Kurata   +15 more
wiley   +1 more source

A Case of Anaplastic Large Cell Lymphoma Misdiagnosed with Keloid

, 2023
Di Kong, Danqi Deng Department of Dermatology, Second Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, 650101, People’s Republic of ChinaCorrespondence: Danqi Deng, Fax +86-871-65351214, Email danqid128@sina.comAbstract: We report a ...
Deng D, Kong D
core  

Chemically Induced Degradation of Anaplastic Lymphoma Kinase (ALK)

, 2018
We present the development of the first small molecule degraders that can induce anaplastic lymphoma kinase (ALK) degradation, including in non-small-cell lung cancer (NSCLC), anaplastic large-cell lymphoma (ALCL), and neuroblastoma (NB) cell lines ...
Katherine A. Donovan (5136575), Radosław P. Nowak (1452139), Eric S. Fischer (5136572), Amanda Loehr (5136569), Magda Bahcall (1463716), Chelsea E. Powell (5136566), Rani E. George (24532), Nathanael S. Gray (150685), Pasi A. Jänne (1277622), Yang Gao (18005), Li Tan (157486)   +10 more
core   +2 more sources

Expression of p63 in anaplastic large cell lymphoma but not in classical Hodgkin\u27s lymphoma

, 2008
Immunohistochemical determination of p63 protein is frequently used in the pathologic diagnosis of nonhematological solid tumors. In malignant hematological disease, p63 expression has been reported in 22% of follicular lymphoma, about 35% of diffuse ...
Weiss, Lawrence M., Bacchi, Carlos E., Gualco, Gabriela   +2 more
core   +1 more source

Poorly differentiated lung adenocarcinomas with concurrent ALK and CD30 expression: a diagnostic pitfall mimicking ALK‐positive anaplastic large‐cell lymphoma

Histopathology, EarlyView.
Poorly differentiated lung adenocarcinomas with concurrent anaplastic lymphoma kinase (ALK) and CD30 expression closely mimic ALK‐positive anaplastic large‐cell lymphoma, creating a significant diagnostic pitfall. Accurate classification requires comprehensive integration of clinical, radiologic, morphologic, immunophenotypic and molecular findings ...
Jietian Jin, Wenjian Cen, Qin Yan, Yangshan Chen, Chaoyun Huang, Yanfeng Feng, Neng Jiang   +6 more
wiley   +1 more source

Brentuximab Vedotin for Refractory Anaplastic Lymphoma Kinase-Negative Anaplastic Large Cell Lymphoma in Leukemic Phase with RUNX3 Overexpression

, 2020
Anaplastic lymphoma kinase (ALK)- negative anaplastic large cell lymphoma (ALCL) is an aggressive CD30-positive non- Hodgkin lymphoma. ALK-ALCL rarely manifests with extensive bone marrow and peripheral blood involvement (known as “leukemic phase”). A 54-
Takehiro Oiwa, Kenji Warigaya, Yusuke Yamashita, Shogo Murata, Hideki Kosako, Masakazu Fujimoto, Toshiki Mushino, Takashi Sonoki, Shin-ichi Murata, Shinobu Tamura, Yoshikazu Hori, Akinori Nishikawa   +11 more
core   +1 more source

An Exploration into the Origins and Pathogenesis of Anaplastic Large Cell Lymphoma, Anaplastic Lymphoma Kinase (ALK)-positive [PDF]

, 2017
T cell Non-Hodgkin lymphoma is a heterogeneous disease ranging from malignancies arising from thymic T cells halted in development, through to mature, circulating peripheral T cells.
Suzanne Turner
core   +2 more sources

Anaplastic large-cell lymphoma.

, 2011
The concept of anaplastic large-cell lymphoma (ALCL) has changed over the years because of a stream of new information and novel understanding regarding the cell of origin, biology, genetics, and clinical features of these neoplasms. This new information
European T. Cell Lymphoma Study Group, Pileri SA, FACCHETTI, Fabio, Inghirami G   +3 more
core   +1 more source