Results 91 to 100 of about 686,182 (220)

ICSH Guidance on Bone Marrow Examination and Reporting

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Examination of the bone marrow (BM) remains fundamental to the diagnosis, classification, prognostication, and monitoring of hematolymphoid and other disorders affecting blood cell production. Since publication of the International Council for Standardization in Haematology (ICSH) guideline in 2008, advances in diagnostic technologies, disease
Wendy N. Erber, Alexandar Tzankov, Olga Pozdnyakova, Hiromichi Matsushita, Gina Zini, Leonie Saft, on behalf of the International Council for Standardization in Haematology   +6 more
wiley   +1 more source

Oncogenic Anaplastic Lymphoma Kinase Rearrangements in Lymphoma

European Oncology & Haematology, 2009
Lymphomas expressing anaplastic lymphoma kinase (ALK) represent two distinct lymphoma entities: ALK-positive T-/null-cell anaplastic large cell lymphoma (ALK+ ALCL) and ALK-positive large B-cell lymphoma (ALK+ LBCL). In both subtypes, the inappropriate expression of ALK is driven by 2p23/ ALK
Iwona Wlodarska, Katrien Van Roosbroeck
openaire   +1 more source

Utility of Fine Needle Aspiration Supernatant for Real‐Time PCR–Based Mutation Analysis in Non–Small Cell Lung Cancer

Diagnostic Cytopathology, Volume 54, Issue 11, Page 805-811, November 2026.
ABSTRACT Background The emergence of personalized therapy and molecular sequencing has significantly transformed the management of advanced non–small cell lung carcinoma (NSCLC). Supernatants obtained from fine needle aspiration (FNA) have been shown to be a reliable source of high‐quality nucleic acid for molecular testing.
Adeyinka Akinsanya, Riley Gorden, Madison Rector, Hamna Muhammad, Melissa Randolph, Matt Sperling, Kemin Xu, Sheila Segura, Omer Saeed, Tieying Hou   +9 more
wiley   +1 more source

Alectinib (Alecensa)-induced reversible grade IV nephrotoxicity: a case report and review of the literature

Journal of Medical Case Reports, 2018
Background Lung cancer is among the top causes of cancer-related mortality in men and is the second most common cancer after breast cancer in women. There are approximately 234,030 new cases of lung cancer and 154,050 deaths from lung cancer in 2018 as ...
P Ramachandran, R Morcus, M Tahir, I Onukogu, B Spinowitz, Jen C Wang   +5 more
doaj   +1 more source

Inflammatory Pseudotumour in Common Seal (Phoca vitulina): A Case Report

Veterinary Medicine and Science, Volume 12, Issue 6, November 2026.
A 19‐year‐old intact male common seal (Phoca vitulina) diagnosed with a chronic ulcer. Microbiology identified Vibrio alginolyticus. Radiography noted phalanx alterations. Macroscopic, histopathological, and immunohistochemical examinations revealed a neoplastic origin with a myofibroblastic phenotype. This report describes the first documented case of
Javier M. De Pablo‐Moreno, Rocío Canales, Mireia Mainez, Nicolás Aradilla, Blanca Chinchilla, Néstor Porras, Ignacio Vargas‐Castro, Antonio Rodríguez‐Bertos   +7 more
wiley   +1 more source

Serial growth plate monitoring in a 3‐month‐old Labrador retriever receiving vinblastine chemotherapy

Veterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Abstract A 3‐month‐old, male, entire Labrador retriever was presented for evaluation of a congenital mast cell tumour of the right pinna. Pinnectomy and regional lymphadenectomy confirmed a high‐grade mast cell tumour with nodal pre‐metastasis. Eight vinblastine chemotherapy treatments were administered over 12 weeks.
Paige A. A. Brown, Kate M. Sippel, Alison Masyr   +2 more
wiley   +1 more source

The role of anaplastic lymphoma kinase in pediatric cancers [PDF]

Cancer Science, 2017
The anaplastic lymphoma kinase (ALK) gene was initially identified as a fusion partner of the nucleophosmin gene in anaplastic large‐cell lymphoma with t(2;5)(p23;q35) translocation, and then described with different genetic abnormalities in a number of tumors. Although ALK is known to be involved in the pathogenesis of neuroblastoma through activating
openaire   +2 more sources

ALK Mutation Status in EGFR-negative Non-small-cell Lung Cancer Patients in Bulgaria

Folia Medica, 2018
Background: Patients with non-small-cell lung cancer (NSCLC) with anaplastic lymphoma kinase (ALK) rearrangement mutation are found to be 3–13%.
Djambazov Slaveyko N., Vekov Toni Y., Mekov Evgeni V., Slavchev Georgi S., Petkov Rosen E., Kostadinov Dimitar T., Konteva Ljubliana T.   +6 more
doaj   +1 more source

Economic value and clinical role of minimally invasive, biopsy‐based diagnostics in non‐small cell lung cancer

Cancer Cytopathology, Volume 134, Issue 10, October 2026.
Abstract Background Precision oncology requires diagnostic sampling that delivers molecularly actionable material quickly and safely. In non‐small cell lung cancer (NSCLC), core‐needle biopsy (CNB) remains common. Yet fine‐needle aspiration (FNA) has re‐emerged with rapid on‐site evaluation (ROSE), optimized cell blocks, and next‐generation sequencing.
Jiayuan Guo, Bo Franzén, Rolf Lewensohn, Martin Hysek, Linus Jönsson   +4 more
wiley   +1 more source

Improved Method for Obtaining Patient‐Derived Glioblastoma Organoid and Primary Cells: A Generic and Simplified Approach for Intracranial Tumor With Minimized Input

CNS Neuroscience &Therapeutics, Volume 32, Issue 10, October 2026.
An improved and simplified method enables the generation of primary tumor cells and tumoroids from the same tissue sample with minimal input, applicable universally to both intracranial and spinal tumors. Comparative analysis of drug screening results with patient follow‐up data allows for the assessment of individual drug sensitivity.
Siyuan Wang, Zhonggang Shi, Chihao Zhu, Dawei Dai, Xi Yang, Zhiyi Zhou, Qianying Qiu, Wenhua Sun, Yifeng Miao, Yongming Qiu   +9 more
wiley   +1 more source