Results 51 to 60 of about 22,869 (310)

Colonic Anastomotic Leakage: Current State of the Problem and Prospects for Early Diagnosis

open access: yesИнновационная медицина Кубани
The article discusses the problem of colonic anastomotic leakage in patients who underwent resection for colorectal cancer. We describe risk factors for colonic anastomotic leakage and diagnostic approaches.
M. A. Chernykh   +2 more
doaj   +1 more source

Real‐Time In Vivo Monitoring of Anastomotic Intestinal Ischemia Using Implantable Resorbable Organic Sensors

open access: yesAdvanced Science, EarlyView.
Resorbable impedance sensors are successfully implanted into porcine small intestinal anastomoses. Impedance was recorded for 2 hours prior, and 2 hours following ischemia induction, and a significant drop in tissue impedance was observed. Abstract Anastomotic failure remains one of the most severe complications in gastrointestinal surgery.
Dennis Wahl   +12 more
wiley   +1 more source

APPLICATION OF TRANSANAL TUBE AFTER ANTERIOR RECTAL RESECTION: IMPACT ON PREVENTION OF “ACHILLES HEEL” IN COLORECTAL SURGERY [PDF]

open access: yesSanamed
Aim: The aim of our study was to investigate the potential reduction in the likelihood of anastomotic leakage occurrence in patients undergoing open anterior resection of the rectum without a protective stoma for stage III adenocarcinoma, by employing a ...
Hodzic Edin   +6 more
doaj   +1 more source

Efficacy of the polyglycolic acid sheet for preventing anastomotic leakage in double-stapling technique anastomosis for left-sided colon or rectal cancer surgery: a propensity score-matched study

open access: yesBMC Surgery, 2023
Background To prevent anastomotic leakage in patients with left-sided colorectal cancer who underwent double-stapling technique (DST) anastomosis, we investigated a new method: DST anastomosis with a polyglycolic acid (PGA) sheet. This procedure has been
Masatsune Shibutani   +4 more
doaj   +1 more source

'Noninvasive' Treatment of Esophagogastric Anastomotic Leakage

open access: yesArchives of Surgery, 1988
To the Editor .—We would like to comment on the interestingbrief communicationby Ofek and Hoffmann. 1 In 1905, Yates 2 concluded that drainage was impossible because of encapsulation of the drain. This remains a problem. Leakage following esophagogastric or esophagojejunal anastomosis is a serious complication with a high mortality rate.
Papadimitriou, J. D.   +2 more
openaire   +3 more sources

PRDM1+ Malignant Cells Mediate an Immunosuppressive Landscape and Resistance to Neoadjuvant Chemoradiotherapy and Immunotherapy in Esophageal Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
Integrated scRNA‐seq, scTCR‐seq analysis, and functional assays identify PRDM1+ malignant epithelial cells with hyper lipid peroxidation characteristics that demonstrate reduced responsiveness to the nICRT treatment. Principal factor PRDM1 activates cysteine metabolism genes to modulate lipid peroxidation (an intrinsic cellular pathway related to ...
Dijian Shen   +12 more
wiley   +1 more source

Elevator‐Like Hollow Channels in Porous Scaffolds Accelerate Vascularized Bone Regeneration via NETs‐Fibrin‐Mediated Macrophage Recruitment

open access: yesAdvanced Science, EarlyView.
This study demonstrates that how hollow‐channel scaffolds promote vascularized bone regeneration via an immunomodulatory mechanism. The channel structures facilitate the formation of a neutrophil extracellular traps‐fibrin scaffold that recruits vascular endothelial growth factor A (VEGF‐A)‐secreting M2 macrophages to drive angiogenesis. Combining this
Guifang Wang   +8 more
wiley   +1 more source

Postoperative non‐steroidal anti‐inflammatory drugs and anastomotic leakage after gastrointestinal anastomoses: Systematic review and meta‐analysis

open access: yesAnnals of Gastroenterological Surgery, 2020
Aim Non‐steroidal anti‐inflammatory drugs (NSAIDs) are commonly used to control postoperative pain; however, their postoperative use has been associated with anastomotic leakage after gastrointestinal surgery.
Supaschin Jamjittrong   +9 more
doaj   +1 more source

Cascade‐Responsive MXene@Cu‐MOF Heterostructure Integrates Antioxidant Activity, Infection Control, and Vascularization for Tracheal Repair

open access: yesAdvanced Science, EarlyView.
A cascade‐responsive MXene@Cu‐MOF/GelMA hydrogel is engineered as a “skeleton–backpack” platform for extensive tracheal repair. The MXene framework scavenges postoperative ROS and converts NIR light into mild hyperthermia, while the Cu‐MOF component provides pH/NIR‐responsive Cu2+ dosing for infection control, angiogenesis, and chondrogenesis.
Liang Guo   +8 more
wiley   +1 more source

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