Results 71 to 80 of about 401,712 (351)

Anatomical Network Comparison of Human Upper and Lower, Newborn and Adult, and Normal and Abnormal Limbs, with Notes on Development, Pathology and Limb Serial Homology vs. Homoplasy [PDF]

open access: yes, 2015
How do the various anatomical parts (modules) of the animal body evolve into very different integrated forms (integration) yet still function properly without decreasing the individual's survival?
A Goswami   +89 more
core   +3 more sources

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

Morphological analysis and clinical significance of the opening of the third coronary artery

open access: yesJournal of Health Sciences, 2022
Introduction: The human heart is in most cases vascularized by two coronary arteries, the right coronary artery (RCA) and the left coronary artery. The supernumerary coronary artery, which arises independently from the right aortic sinus and passes ...
Almira Lujinović   +5 more
doaj   +1 more source

Anatomical variations of the azygos venous system:Classification and clinical relevance [PDF]

open access: yes, 2016
The azygos venous system is highly variable in terms of its origin, course, communications, tributaries and termination of the associated veins: this study aimed to classify these anatomical variations.
Dahran, Naief, Soames, Roger
core   +2 more sources

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Age-dependent expression of DNMT1 and DNMT3B in PBMCs from a large European population enrolled in the MARK-AGE study [PDF]

open access: yes, 2016
Aging is associated with alterations in the content and patterns of DNA methylation virtually throughout the entire human lifespan. Reasons for these variations are not well understood.
Bacalini, MARIA GIULIA   +26 more
core   +2 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Heschl's gyrus is more sensitive to tone level than non-primary auditory cortex [PDF]

open access: yes, 2002
Previous neuroimaging studies generally demonstrate a growth in the cortical response with an increase in sound level. However, the details of the shape and topographic location of such growth remain largely unknown.
Alan R Palmer   +66 more
core   +1 more source

Anatomical variations during mastoidectomy

open access: yesKafkas Journal of Medical Sciences, 2011
RESULTS: In 8 (2.6%) patients, the entrance to mastoid antrum was troublesome due to Korner septum. In three patients a dehiscence in the bony canal were noted which proned these patients to possible facial nerve injury. In 4 (1.3%) patients, dura was open to surgical cavity due to dehiscence of the tegmen timpany and in 3 (1%) patients, dura was as ...
Zeliha Kapusuz   +3 more
openaire   +1 more source

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