Results 181 to 190 of about 1,836,350 (356)

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

The anatomy of internal interference in public service media: How do journalists interpret whether editorial interference constitutes unacceptable encroachment on their autonomy? [PDF]

Marína Urbániková
openalex   +1 more source

A Study of Anatomy & histopathology with effect of spiral artery remodeling and Vitamin D receptors (VDR) in preeclampsia

, 2022
Ehab Kamal Ali*
openalex   +2 more sources

Painting anatomy on anatomy.

The Journal of biocommunication, 1996
Painting anatomical features on a model's skin to delineate internal structures is a medical illustration technique that rarely has been used. Yet it seems to have potential where the scientific point involves muscles, tendons, nerves, blood vessels, bones and other tissues that either produce an external configuration on the body surface or lie ...
openaire   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

A Rare Anatomical Variant Dual Radial Digital Nerves in the Right Ring Finger: Consideration in Hand Dissection. [PDF]

J Hand Surg Glob Online
Vlassis N, Schermerhorn JT, Rambau G.
europepmc   +1 more source

The “Hand as Foot” teaching method in variants of the brain Willis circle anatomy

, 2022
Tao Xiong, Weihua Di, Huiying Zuo, Cuijie Shao   +3 more
openalex   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Back to the anatomy lab: a forgotten foundation or an ongoing necessity? [PDF]

BMC Med Educ
Temi̇zsoy Korkmaz F, Çandir Gürses BN, Balci Yapalak AN, Gürses İA.   +3 more
europepmc   +1 more source

The utility of customised tissue probability maps and templates for patients with idiopathic normal pressure hydrocephalus: a Computational Anatomy Toolbox (CAT12) study [PDF]

Shigenori Kanno, Jun‐Yan Liu, Ai Kawamura, Shoko Ota, Nobuko Kawakami, Chifumi Iseki, Kazuo Kakinuma, Shiho Matsubara, Kazuto Katsuse, Kazushi Sato, Takashi Takeuchi, Yoshitaka Tanaka, Hiroyasu Kodama, Tatsuo Nagasaka, Masahiro Sai, Hayato Odagiri, Mioko Saito, Kentaro Takanami, Shunji Mugikura, Kyoko Suzuki   +19 more
openalex   +1 more source