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Analytical Methods for Anatoxin-a Determination: A Review [PDF]

open access: yesToxins
Anatoxin-a (ATX-a) is a potent neurotoxin produced by several species of cyanobacteria whose exposure can have direct consequences, including neurological disorders and death. The increasing prevalence of harmful cyanobacterial blooms makes the detection
Cristina Plata-Calzado   +3 more
doaj   +6 more sources

Microcystin Prevalence throughout Lentic Waterbodies in Coastal Southern California [PDF]

open access: yesToxins, 2017
Toxin producing cyanobacterial blooms have increased globally in recent decades in both frequency and intensity. Despite the recognition of this growing risk, the extent and magnitude of cyanobacterial blooms and cyanotoxin prevalence is poorly ...
Meredith D. A. Howard   +9 more
doaj   +5 more sources

Developmental neurotoxicity of an anatoxin-a-producing cyanobacteria (Aphanizomenon gracile) lysate to zebrafish (Danio rerio) [PDF]

open access: yesFrontiers in Microbiology
Harmful cyanobacterial blooms occur frequently worldwide with serious environmental impacts. Many detrimental cyanobacteria are well known for their potential to synthesize various cyanotoxins, posing significant threats to aquatic ecosystems and public ...
Chang Liu   +10 more
doaj   +2 more sources

Within-Mat Variability in Anatoxin-a and Homoanatoxin-a Production among Benthic Phormidium (Cyanobacteria) Strains

open access: yesToxins, 2012
Benthic Phormidium mats can contain high concentrations of the neurotoxins anatoxin-a and homoanatoxin-a. However, little is known about the co-occurrence of anatoxin-producing and non-anatoxin-producing strains within mats.
Roger G. Young   +6 more
doaj   +3 more sources

The Chemistry and Pharmacology of Anatoxin-a and Related Homotropanes with respect to Nicotinic Acetylcholine Receptors

open access: yesMarine Drugs, 2006
: This chapter covers the chemistry and nicotinic pharmacology of naturally occurring homotropane alkaloids, with an emphasis of anatoxin-a. In addition to anatoxin-a, homoanatoxin and pinnamine, as well as the major classes of synthetic derivatives of ...
Timothy Gallagher, Susan Wonnacott
doaj   +3 more sources

Detection of Anatoxins in Human Urine by Liquid Chromatography Triple Quadrupole Mass Spectrometry and ELISA [PDF]

open access: yesToxins
Harmful cyanobacterial blooms are becoming more common and persistent around the world. When in bloom, various cyanobacterial strains can produce anatoxins in high concentrations, which, unlike other cyanobacterial toxins, may be present in clear water ...
Brady R. Cunningham   +4 more
doaj   +2 more sources

Evaluation of Genotoxic and Hemolytic Effects of Aphanizomenon flos-aquae and Microcystis aeruginosa Biomass Extracts on Human Blood Cells In Vitro [PDF]

open access: yesMicroorganisms
This study explores the in vitro effects of cyanotoxins from the methanolic extract of the cyanobacteria Aphanizomenon flos-aquae and Microcystis aeruginosa on human blood cells, with samples drawn from the Gruža reservoir in Serbia. These cyanobacteria,
Nevena B. Đorđević   +6 more
doaj   +2 more sources

Assessment of the Effects of Anatoxin-a In Vitro: Cytotoxicity and Uptake [PDF]

open access: yesToxins
Anatoxin-a (ATX-a) is a cyanotoxin whose toxicological profile has been underinvestigated in comparison to other cyanotoxins such as microcystins (MCs) or cylindrospermopsin (CYN).
Cristina Plata-Calzado   +3 more
doaj   +2 more sources

A cohesive Microcoleus strain cluster causes benthic cyanotoxic blooms in rivers worldwide [PDF]

open access: yesWater Research X
Over the last two decades, proliferations of benthic cyanobacteria producing derivatives of anatoxin-a have been reported in rivers worldwide. Here, we follow up on such a toxigenic event happening in the Areuse river in Switzerland and investigate the ...
Pilar Junier   +14 more
doaj   +2 more sources

Confirmation Using Triple Quadrupole and High-Resolution Mass Spectrometry of a Fatal Canine Neurotoxicosis following Exposure to Anatoxins at an Inland Reservoir

open access: yesToxins, 2022
Cyanobacterial blooms are often associated with the presence of harmful natural compounds which can cause adverse health effects in both humans and animals. One family of these compounds, known as anatoxins, have been linked to the rapid deaths of cattle
Andrew D. Turner   +9 more
doaj   +1 more source

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