Results 211 to 220 of about 23,269,289 (245)

Enantioselective synthesis of (+)-anatoxin-a via enyne metathesis

Tetrahedron, 2004
AbstractFor Abstract see ChemInform Abstract in Full Text.
Jehrod B. Brenneman, Rainer Machauer, Stephen F. Martin   +2 more
openaire   +1 more source

Risk quick sketch: Soil captured most anatoxin-a and microcystin-RR rather than cylindrospermopsin and microcystin-LA/-LY.

Science of the Total Environment
Cyanobacteria proliferate in warm, nutrient-rich environments and release toxic secondary metabolites (e.g., cyanotoxins, anabaenopeptins, etc.) into natural waters. Using the toxic secondary metabolites -contaminated water to irrigate crops could expose
Yanyan Zhang, S. V. Duy, J. Whalen, Gabriel Munoz, Sébastien Sauvé   +4 more
semanticscholar   +1 more source

Morphofunctional changes in the animal organisms under oral exposure to anatoxin-a in subchronic experimental settings

Toxicological Review
Introduction. Anatoxin-a (2-acetyl-9-azabicyclo[4.2.1]non-2-ene) produced by blue-green algae of the genera Dolichospermum (Anabaena), Aphanizomenon, Cylindrospermum, Oscillatoria, Planktothrix and Raphidiopsis, which are widely spread in the reservoir ...
O. Sinitsyna, V.V. Turbinskii, M.V. Pushkareva, N. V. Kuz, G. Masaltsev, M. Shiryaeva, T. M. Ryashentseva, E. A. Valtseva, M. V. Vostrikova   +8 more
semanticscholar   +1 more source

anatoxin A poisoning

CABI Compendium, 2022
This datasheet on anatoxin A poisoning covers Identity.

semanticscholar   +1 more source

A short and enantioselective synthesis of (+)-Anatoxin-a

Tetrahedron Letters, 1992
Abstract A short and enantioselective total synthesis of the neurotoxic alkaloid (+)-Anatoxin-a ( 1 ) from the L-pyroglutamic acid derivative 2 is described. The key step involves an intramolecular cyclisation of an N-tosyl iminium ion derived from the corresponding α-methoxy sulfonamide.
Peter Somfai, Jens Åhman
openaire   +2 more sources

Synthesis of (+)-anatoxin-a using enyne metathesis

Tetrahedron Letters, 2004
Abstract Synthesis of N -tosylanatoxin- a was achieved by metathesis of enyne in cis -substituents on a pyrrolidine derivative. Metathesis reactions of enyne having terminal alkyne using various ruthenium-carbene complexes did not give a good results. However, when the terminal alkyne was protected with a TMS group, the reaction proceeded smoothly
Miwako Mori, Tomohiro Tomita, Yoichi Kita, Tsuyoshi Kitamura   +3 more
openaire   +1 more source

Quantification of cylindrospermopsin, anatoxin-a and homoanatoxin-a in cyanobacterial bloom freshwater using direct injection/SPE coupled with UPLC-MS/MS.

Science of the Total Environment, 2020
Analytical methods based on direct injection (DI) and solid phase extraction (SPE) coupled with ultrahigh performance liquid chromatography-tandem mass spectrometry (UPLC- MS/MS) were developed for the determination of anatoxin-a (ATX-a ...
N. H. Tran, Yiwen Li, M. Reinhard, Kwan Chien Goh, Nur Hanisah binte Sukarji, Luhua You, Yiliang He, K. Gin   +7 more
semanticscholar   +1 more source

Biosynthesis of anatoxin-a and analogues (anatoxins) in cyanobacteria

Toxicon, 2014
Freshwater cyanobacteria produce secondary metabolites that are toxic to humans and animals, the so-called cyanotoxins. Among them, anatoxin-a and homoanatoxin-a are potent neurotoxins that are agonists of the nicotinic acetylcholine receptor. These alkaloids provoke a rapid death if ingested at low doses. Recently, the cluster of genes responsible for
Annick, Méjean, Guillaume, Paci, Valérie, Gautier, Olivier, Ploux   +3 more
openaire   +2 more sources

Early indicators of behavioral and physiological disturbances in Daphnia magna (Cladocera) induced by cyanobacterial neurotoxin anatoxin-a.

Science of the Total Environment, 2019
The majority of reports on the toxic effect of cyanobacterial metabolites on the freshwater invertebrates is based on determination of two endpoints: mortality or immobilization. However, detection of sub-lethal effects requires more sensitive indicators
A. Bownik, B. Pawlik-Skowrońska
semanticscholar   +1 more source

Photocatalytic degradation of microcystin-LR and anatoxin-a with presence of natural organic matter using UV-light emitting diodes/TiO2 process

Journal of Water Process Engineering, 2020
Cyanotoxins are released into water bodies when cyanobacterial blooms occur. Representative cyanotoxins are microcystin-LR (MC-LR), which is one of the most-frequently detected, and anatoxin-a (ANTX), threatening human health through the liver damage and
Boram Yang, Hee-Deung Park, S. Hong, Sang‐hyup Lee, Jeong-Ann Park, J. Choi   +5 more
semanticscholar   +1 more source