Results 221 to 230 of about 23,269,289 (245)

Potential developmental toxicity of anatoxin‐a, a cyanobacterial toxin

Journal of Applied Toxicology, 2005
AbstractSome 2000 species of cyanobacteria (blue‐green algae) occur globally in aquatic habitats. They are able to survive under a wide range of environmental conditions and some produce potent toxins. Toxin production is correlated with periods of rapid growth (blooms) and 25%–70% of blooms may be toxic.
E H, Rogers, E S, Hunter, V C, Moser, P M, Phillips, J, Herkovits, L, Muñoz, L L, Hall, N, Chernoff   +7 more
openaire   +2 more sources

First report of saxitoxins and anatoxin-a production by cyanobacteria from Lithuanian lakes

, 2020
This study describes the first report on saxitoxins (STXs) and anatoxin-a (ANTX-a) production by cyanobacteria in Lithuanian lakes. Seasonal fluctuation patterns for neurotoxins were determined in samples collected from eutrophic lakes during July ...
J. Karosienė, Ksenija Savadova-Ratkus, Anna Toruńska-Sitarz, J. Koreivienė, J. Kasperovičienė, Irma Vitonytė, A. Błaszczyk, H. Mazur-Marzec   +7 more
semanticscholar   +1 more source

ChemInform Abstract: An Efficient Synthesis of (+)‐Anatoxin‐a.

ChemInform, 1993
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
M. SKRINJAR, C. NILSSON, L.‐G. WISTRAND   +2 more
openaire   +1 more source

Effects of cylindrospermopsin, its decomposition products, and anatoxin-a on human keratinocytes.

Science of the Total Environment, 2020
Toxins produced by cyanobacteria (cyanotoxins) are among the most dangerous natural compounds. In recent years, there have been many published papers related to the toxic alkaloids cylindrospermopsin (CYN) and anatoxin-a (ANTX-a), which are synthesized ...
Michał Adamski, E. Zimoląg, Ariel Kaminski, J. Drukała, J. Białczyk   +4 more
semanticscholar   +1 more source

Synthetic and stereochemical studies directed towards anatoxin-a

Journal of the Chemical Society, Perkin Transactions 1, 1991
The synthesis and stereocontrolled AgI-catalysed cyclisation of a series of allenic amino esters 8a–e is described. For compounds 8a–d the cis-2,5-disubstituted pyrrolidine 9 is formed exclusively but the primary amine 8e undergoes cyclisation nonselectively to give a mixture of cis- and trans-pyrrolidines 9e and 10e.
Nicholas J. S. Huby, Richard G. Kinsman, David Lathbury, Peter G. Vernon, Timothy Gallagher   +4 more
openaire   +1 more source

Behavioural effects of anatoxin, a potent nicotinic agonist, in rats

Neuropharmacology, 1992
Preliminary behavioural studies with the nicotinic agonist (+)-anatoxin have been carried with procedures sensitive to (-)-nicotine. In experimentally naive rats, (+)-anatoxin decreased locomotor activity; this effect resembled that of (-)-nicotine, but it was not blocked by mecamylamine.
I P, Stolerman, E X, Albuquerque, H S, Garcha   +2 more
openaire   +2 more sources

Analysis of anatoxin-a in aqueous samples

Chromatographia, 1997
Anatoxin-a is a naturally occurring, potent neurotoxin produced by some species of blue-green algae. Release of anatoxin-a into water bodies on cell lysis is of concern to farmers, whose livestock may be affected by drinking contaminated water; to recreational users of reservoirs where a blue-green algal scum is present; and to water companies, who ...
openaire   +1 more source

Quantitative Structure-activity Relationships Of (+)-anatoxin-a Derivatives

Natural Product Letters, 1994
Abstract The QSAR of a series of 21 nicotinic agonists, anatoxin-a (AnTX) and derivatives, was investigated using multivariate statistical techniques. Physicochemical properties were calculated for the compounds using computational chemistry. In order to model the structures it was necessary to choose a common conformation.
Gallagher, TC, Manallack, DT, Ellis, DD, Thompson, PE, Livingstone, DJ   +4 more
openaire   +1 more source

ChemInform Abstract: Synthetic Approaches to Anatoxin‐a

ChemInform, 1996
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
openaire   +1 more source

Anatoxin-a-evoked [3H]dopamine release from rat striatal synaptosomes

Neuropharmacology, 1995
Presynaptic nicotinic acetylcholine receptors on striatal nerve terminals modulate the release of dopamine. Using rat striatal synaptosomes loaded with [3H]dopamine, we have characterized the action of the selective nicotinic agonist, (+/-)anatoxin-a, with respect to [3H]dopamine release, in order to explore the mechanisms coupling nicotinic receptor ...
Soliakov, L, Gallagher, TC, Wonnacott, S
openaire   +2 more sources