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Clinician views concerning the prevalence and impact of granulomas on the diagnosis, management, and outcomes of ANCA-associated vasculitis. [PDF]
Junek M +5 more
europepmc +1 more source
Predicting prognosis in ANCA-associated vasculitis with kidney involvement. [PDF]
Maalouli C +12 more
europepmc +1 more source
Repeat kidney biopsy reveals new-onset IgA nephropathy in a patient with ANCA-associated vasculitis. [PDF]
Iwami S +8 more
europepmc +1 more source
Avacopan for the Treatment of ANCA-Associated Vasculitis
BACKGROUND: The C5a receptor inhibitor avacopan is being studied for the treatment of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis. METHODS: In this randomized, controlled trial, we assigned patients with ANCA-associated vasculitis in a 1:1 ratio to receive oral avacopan at a dose of 30 mg twice daily or oral prednisone on a ...
Peter Merkel +2 more
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Biologics for ANCA-Associated Vasculitis
Inflammation & Allergy-Drug Targets, 2014The antineutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAV) are a group of necrotizing vasculitides with a potential fatal outcome. Conventional therapy is based on the use of glucocorticoids (GCs) and cyclophosphamide (CYC), which is associated with severe toxic effects and is unable to control the disease activity in some refractory ...
Murgia G +3 more
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The Future of ANCA-associated Vasculitis
Rheumatic Disease Clinics of North America, 2010The introduction of cyclophosphamide for treatment and the detection of antineutrophil cytoplasmatic antibodies (ANCA) as a seromarker for ANCA-associated vasculitis (AAV) have been the most important milestones in the history of AAV. Nevertheless, there are still many issues to resolve to fully understand the pathogenesis of AAV and to improve patient
Julia U, Holle +2 more
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