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Novel Therapies for ANCA-associated Vasculitis
Current Rheumatology Reports, 2021The purpose of this review is to discuss the most recent evidence on the treatment innovations and future prospective in the management of anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAVs).In AAV, a growing body of research is available on novel treatment options for remission induction and to clarify some uncertainties ...
Monti S. +5 more
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Pathology of ANCA-associated vasculitis
Clinical and Experimental Nephrology, 2012According to the recent 2012 Chapel Hill Consensus Conference, ANCA-associated vasculitis is classified in the group of small vessel vasculitis. Pauci-immune necrotizing crescentic glomerulonephritis is the morphological hallmark of ANCA-associated vasculitis.
Ferrario, F, Vanzati, A, PAGNI, FABIO
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An update on the epidemiology of ANCA-associated vasculitis.
Rheumatology, 2020ANCA-associated vasculitis (AAV) includes granulomatosis with polyangiitis, microscopic polyangiitis and eosinophilic granulomatosis with polyangiitis.
A. Mohammad
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Autoantibodies in ANCA-associated Vasculitis
Rheumatic Disease Clinics of North America, 2010Antineutrophil cytoplasmic autoantibody (ANCA)-associated vasculitides are systemic or more limited conditions characterized by necrotizing destruction of small and medium-sized vessels (eg, capillaries, venules, and arterioles). ANCAs are the most predominant autoantibodies in patients affected by vasculitis, but other autoantibodies may also occur ...
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The Future of ANCA-associated Vasculitis
Rheumatic Disease Clinics of North America, 2010The introduction of cyclophosphamide for treatment and the detection of antineutrophil cytoplasmatic antibodies (ANCA) as a seromarker for ANCA-associated vasculitis (AAV) have been the most important milestones in the history of AAV. Nevertheless, there are still many issues to resolve to fully understand the pathogenesis of AAV and to improve patient
Julia U, Holle +2 more
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Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia, 2002
ANCA-associated vasculitis. The term "antineutrophil cytoplasm antibody (ANCA)- associated vasculitis" (AASV) ihighers generally used to include primary vasculitis syndromes in which circulating ANCA against proteinase 3 (PR3) and myeloperoxidase (MPO) are commonly found.
SINICO, RENATO ALBERTO +3 more
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ANCA-associated vasculitis. The term "antineutrophil cytoplasm antibody (ANCA)- associated vasculitis" (AASV) ihighers generally used to include primary vasculitis syndromes in which circulating ANCA against proteinase 3 (PR3) and myeloperoxidase (MPO) are commonly found.
SINICO, RENATO ALBERTO +3 more
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Biomarkers in ANCA-Associated Vasculitis
Current Rheumatology Reports, 2013Despite recent advances in the treatment of antineutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis (AAV), relapse remains common and patients often experience a variable clinical course after initial treatment. New biomarkers are needed to aid the management of these complex diseases.
Lindsay, Lally, Robert F, Spiera
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The History of ANCA-associated Vasculitis
Rheumatic Disease Clinics of North America, 2010An essential early step toward understanding vasculitis was recognition in 1948 of the differences between the small artery disease of polyarteritis, essentially sparing the glomerulus and lungs, and disease of glomerular vessels and small veins, often involving the lungs.
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Vasculitis for the internist: focus on ANCA-associated vasculitis
Internal and Emergency Medicine, 2017Vasculitides comprise several diseases affecting vessels of different sizes, mainly arteries, but also capillaries and veins. Antineutrophil cytoplasm antibody-associated vasculitides (AAVs) belong to the systemic necrotizing small-vessel vasculitis group that comprises granulomatosis with polyangiitis, microscopic polyangiitis and eosinophilic ...
Benjamin, Chaigne, Loïc, Guillevin
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