Results 41 to 50 of about 151,234 (305)

Damage to the organ of hearing and upper respiratory tract in vasculitis associated with antineutrophil cytoplasmic antibodies

Klinicist
Antineutrophil cytoplasmic antibodies associated vasculitis (ANCA-AV) is a systemic necrotizing granulomatous vasculitis affecting mainly small-caliber vessels.
A. A. Klimenko, T. K. Loginova, Yu. M. Sahakyan, V. I. Petrikova, D. Yu. Andriyashkina   +4 more
doaj   +1 more source

A Qualitative Analysis of Patient Perspectives and Preferences in Lupus Management to Guide Lupus Guidelines Development

Arthritis Care &Research, EarlyView.
Objective A patient‐centered approach for chronic disease management, including systemic lupus erythematosus (SLE), aligns treatment with patients’ values and preferences, leading to improved outcomes. This paper summarizes how patient experiences, perspectives, and priorities informed the American College of Rheumatology (ACR) 2024 Lupus Nephritis (LN)
Shivani Garg, Izzy Hartel, Lisa R. Sammaritano, Anca Askanase, Bonnie L. Bermas, Maria Dall'Era, Alí Duarte‐García, Victoria P. Werth, Brad Rovin, Reem A. Mustafa, Amy S. Turner, Bené Williams, Brian L. Ung, Hiya Bhavsar, Monique C. Gore‐Massy, Nahirannette Pulido, Natacha Guerrero, Natalie M. Smith, Wambui Machua, Linda T. Hiraki, Mary Beth Son   +20 more
wiley   +1 more source

Yarsagumba Collection and Marketing: a Key Income Source of People in Api Nampa Conservation Area, Darchula, Nepal [PDF]

, 2020
Yarsagumba the Himalayan gold rush is the major part of the economy of the himalayan people in the Darchula distict. Our study was conducted in Khandeshwori region of the the Darchula district to quantify the contribution of Yarsagumba on the total ...
Bhatta, J. (Jagdish), Kandel, K. (Khagendra), Karki, R. (Renuka), Kunwar, A. (Aashish), Pant, P. K. (Prakash), Panthi, S. (Shambhu)   +5 more
core  

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

Advanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao, Qinyuan Liu, Zhongwei Xin, Zhiyao Zhou, Mingjie Lin, Di Chen, Zhixing Hao, Yongyuan Chen, Wenxuan Wu, Shuyang Zhang, Xiaoke Chen, Xia Xu, Jinfan Li, Wei Lin, Yuhao Lu, Dang Wu, Pin Wu   +16 more
wiley   +1 more source

The Cognitive Triad Inventory (CTI) psychometric properties on a Romanian sample

BMC Psychology
Background This study aims to develop the Romanian version of the Cognitive Triad Inventory (CTI) by documenting the Romanian translation of the instrument items and its psychometric characteristics. We were concerned with the items’ adaptation, analyzed
Anca -Monica Puia, Alexandru Mihalcea, Violeta Ștefania Rotărescu   +2 more
doaj   +1 more source

Plasma exchange and glucocorticoids to delay death or end-stage renal disease in anti-neutrophil cytoplasm antibody-associated vasculitis: PEXIVAS non-inferiority factorial RCT

Health Technology Assessment, 2022
Background: Anti-neutrophil cytoplasm antibody-associated vasculitis is a multisystem, autoimmune disease that causes organ failure and death. Physical removal of pathogenic autoantibodies by plasma exchange is recommended for severe presentations, along
David Jayne, Michael Walsh, Peter A Merkel, Chen Au Peh, Wladimir Szpirt, Xavier Puéchal, Shouichi Fujimoto, Carmel Hawley, Nader Khalidi, Rachel Jones, Oliver Flossmann, Ron Wald, Louis Girard, Adeera Levin, Gina Gregorini, Lorraine Harper, William Clark, Christian Pagnoux, Ulrich Specks, Lucy Smyth, Toshiko Ito-Ihara, Janak de Zoysa, Biljana Brezina, Andrea Mazzetti, Carol A McAlear, Donna Reidlinger, Samir Mehta, Natalie Ives, Elizabeth A Brettell, Hugh Jarrett, Keith Wheatley, Elizabeth Broadhurst, Alina Casian, Charles D Pusey   +33 more
doaj   +1 more source

Soybean Auxin Transporter PIN3 Regulates Nitrate Acquisition to Improve Nitrogen Use and Seed Traits

Advanced Science, EarlyView.
Xu et al. discovers that switching off auxin transporters in soybean, PIN3a and PIN3b, disrupts auxin flow; this triggers ARF‐STF3/4 signal cascade to activate the nitrate importer NPF2.13 and soil nitrogen acquisition. Multi‐year field trials show edited soybeans maintain yield with higher oil content, offering a potential genetic route to improve ...
Huifang Xu, Shiyu Huang, Jie Wang, Tian Wang, Qingqing Han, Kexin Wu, Zhen Gao, Xiaolei Shi, Tianli Tu, Ming Wang, Laimei Huang, Jiaomei Chen, Yunqi Liu, Yumei Zhang, Guoqiang Lin, Zhichang Chen, Xu Chen   +16 more
wiley   +1 more source

Exploring ANCA Pathogenicity in Ulcerative Colitis: A Case Report Highlighting the Risk of Progression to ANCA-Associated Vasculitis

European Journal of Case Reports in Internal Medicine
This case report addresses the association between ulcerative colitis and ANCA vasculitis-associated alveolar hemorrhage. A 20-year-old African woman with a history of ulcerative colitis with high PR3-ANCAs titer presented to the emergency department for
Abir Hamid, Frederic Vandergheynst, Maxime Ilzkovitz   +2 more
doaj   +1 more source

Infective endocarditis with antineutrophil cytoplasmic antibody: report of 13 cases and literature review.

PLoS ONE, 2014
ObjectiveChronic infections tend to induce the production of antineutrophil cytoplasmic antibody (ANCA). Infective endocarditis (IE) has been reported to exhibit positive ANCA tests and to mimic ANCA-associated vasculitis, which may lead to a ...
Chun-Mei Ying, Dong-Ting Yao, Hui-Hua Ding, Cheng-De Yang   +3 more
doaj   +1 more source

Hypocomplementemia is associated with more severe renal disease and worse renal outcomes in patients with ANCA-associated vasculitis: a retrospective cohort study

Renal Failure, 2020
Background The complement system has been recently proposed to play an important role in the pathogenesis of ANCA-associated vasculitis (AAV). This study evaluated the value of serum and kidney deposited C3 in predicting renal outcomes in AAV.
Aglaia Chalkia, Konstantinos Thomas, Panagiota Giannou, Alexandros Panagiotopoulos, Emilia Hadziyannis, Athanasia Kapota, Harikleia Gakiopoulou, Dimitrios Vassilopoulos, Dimitrios Petras   +8 more
doaj   +1 more source