Results 51 to 60 of about 143,542 (269)

Dietary habits and lifestyle in school-aged children from Bucharest, Romania [PDF]

open access: yes, 2018
Background. This study evaluated the difference between boys and girls in terms of nutritional status, lifestyle, and dietary habits during school life. Materials and Methods.
Andronache, Liliana F.   +11 more
core   +3 more sources

Relative Exchangeable Copper Confirms Wilson Disease and Supports Reclassification of the ATP7B p.Met665Ile Variant With Conflicting Pathogenicity Evidence

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Wilson disease (WD) is an autosomal recessive disorder of copper metabolism caused by ATP7B mutations. Diagnosis is usually straightforward in symptomatic patients, but can be challenging in children and adolescents with mild liver disease, borderline urinary copper excretion, or inconclusive genetic findings.
Emanuele Nicastro   +10 more
wiley   +1 more source

Significance of anti-neutrophil cytoplasmic antibodies in systemic sclerosis

open access: yesArthritis Research & Therapy, 2019
Background Up to 12% of patients with systemic sclerosis (SSc) have anti-neutrophil cytoplasmic antibodies (ANCA). However, the majority of these patients do not manifest ANCA-associated vasculitis (AAV) and the significance of ANCA in these patients is ...
Jayne Moxey   +12 more
doaj   +1 more source

Intermediate Moduli Spaces of Stable Maps [PDF]

open access: yes, 2004
We describe the Chow ring with rational coefficients of Mbar_{0,1}(P^n,d) as the subring of invariants of a ring B(Mbar_{0,1}(P^n,d);Q), relative to the action of the group of symmetries S_d.
Mustata, Andrei, Mustata, Magdalena Anca
core   +5 more sources

Establishment of a mouse model of propylthiouracil‐induced antineutrophil cytoplasmic antibody‐associated vasculitis

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This graphical abstract summarizes our study in which we established a novel murine model of antineutrophil cytoplasmic antibody (ANCA)‐associated vasculitis. Neutrophil recruitment was induced using thioglycolate, followed by timed administration of propylthiouracil and phorbol 12‐myristate 13‐acetate to generate DNase I‐resistant neutrophil ...
Sakiko Masuda   +9 more
wiley   +1 more source

Risk Factors for Relapse in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis Among Patients With Relapse After Induction of Remission With Rituximab. [PDF]

open access: yesArthritis Rheumatol
Objective The objective of the study was to determine risk factors for relapse of antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis (AAV) after reinduction of remission with rituximab and discontinuation of maintenance therapy. Methods This is a post hoc analysis of the RITAZAREM clinical trial.
Romich E   +10 more
europepmc   +2 more sources

Prognostic Factors of Renal Involvement in Systemic Sclerosis [PDF]

open access: yes, 2018
Background/Aims: Renal involvement is common in systemic sclerosis (SSc), including asymptomatic reduction of glomerular filtration rate (GFR), increased renal resistance indices, scleroderma renal crisis (SRC) and ANCA-associated vasculitis. The aim was
Barbano, Biagio   +5 more
core   +2 more sources

Interleukin‐5, Eosinophils, and Interleukin‐5 Pathway Inhibitors in Eosinophilic Granulomatosis With Polyangiitis

open access: yesArthritis &Rheumatology, EarlyView.
Interlukin‐5 (IL‐5) plays a crucial role in the pathogenesis of eosinophilic granulomatosis with polyangiitis (EGPA) by promoting eosinophil differentiation, activation, and survival. We present here a typical case of EGPA in which treatment with IL‐5 pathway inhibitors is prescribed, showing to be beneficial for the patient.
Alvise Berti, Christian Pagnoux
wiley   +1 more source

Automatic Reading of ANCA-Slides: Evaluation of the AKLIDES System

open access: yesClinical and Developmental Immunology, 2012
The ANCA consensus prescribes screening by indirect immunofluorescence on neutrophils. We evaluated the first automated ANCA-pattern recognition system. C-ANCA and P-ANCA samples were selected from patients with ANCA-associated vasculitis (AAV).
Jan Damoiseaux   +4 more
doaj   +1 more source

Simultaneous automated screening and confirmatory testing for vasculitis-specific ANCA. [PDF]

open access: yesPLoS ONE, 2014
Anti-neutrophil cytoplasmic antibodies (ANCA) are the serological hallmark of small vessel vasculitis, so called ANCA-associated vasculitis. The international consensus requires testing by indirect immunofluorescence (IIF) on human ethanol-fixed ...
Mandy Sowa   +13 more
doaj   +1 more source

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