Results 51 to 60 of about 88,572 (244)

Different Types of ANCA Determine Different Clinical Phenotypes and Outcome in ANCA-Associated Vasculitis (AAV)

Frontiers in Medicine, 2022
AimAccumulating evidence supports the use of antineutrophil cytoplasmic antibody (ANCA) type to classify different clinical entities. We aimed to evaluate whether the presence and type of ANCA determine different diseases, based on clinical phenotypes ...
Kostas Bantis, Maria J. Stangou, Savvas Kalpakidis, Christina Nikolaidou, George Lioulios, Zoi Mitsoglou, Fotini Iatridi, Asimina Fylaktou, Aikaterini Papagianni   +8 more
doaj   +1 more source

Oral vancomycin solution is superior to capsule in inducing clinical biomarker and endoscopic remission in children with atypical ulcerative colitis

British Journal of Clinical Pharmacology, EarlyView.
Aims Atypical colitis (presenting reverse gradient colitis, backwash ileitis or rectal sparing) is associated with primary sclerosing cholangitis–ulcerative colitis (PSC). Oral vancomycin has been used to manage paediatric atypical colitis with/without confirmed PSC. Different preparations had shown different efficacy.
Laura Räisänen, Fariha Balouch, Claire Reilly, Christopher Burgess, Peter Lewindon   +4 more
wiley   +1 more source

ANCA-associated vasculitis mission incomplete

, 2018
Over the last decades, introduction of high-dose corticosteroids and immunosuppressive agents and later rituximab into the current algorithms for remission induction and maintenance treatment resulted in a tremendous improvement in the survival of ...
Anna Ivanova (6059813)
core   +1 more source

Patients with Chronic Inflammatory Diseases Can Experience Higher Exposure of Small Molecule Drugs than Healthy Volunteers: An Analysis of Recently Approved Drugs

Clinical Pharmacology &Therapeutics, EarlyView.
Chronic inflammation has long been known to downregulate the activity of certain cytochrome P450 (CYP) enzymes—the main enzymes responsible for the phase I metabolism of many small molecule drugs—potentially leading to higher exposures in patients with chronic inflammatory diseases compared to healthy volunteers. Neglecting this potential difference in
Johannes Tillil, Sathej Gopalakrishnan, Jennifer Dong, Karthik Venkatakrishnan, Charlotte Kloft, Wilhelm Huisinga, Lena Klopp‐Schulze   +6 more
wiley   +1 more source

Localizing value of ecstatic phenomenon in epilepsy surgery: A systematic review

Epileptic Disorders, EarlyView.
Abstract Objective A systematic review was conducted to synthesize current anatomo‐clinical correlations of ecstatic symptoms in focal epilepsy, aiming to provide evidence‐based guidance for interpreting this ictal semiology during presurgical evaluation.
Mihai Dragos Maliia, Fabrice Bartolomei, Fabienne Picard   +2 more
wiley   +1 more source

Automatic Reading of ANCA-Slides: Evaluation of the AKLIDES System

Clinical and Developmental Immunology, 2012
The ANCA consensus prescribes screening by indirect immunofluorescence on neutrophils. We evaluated the first automated ANCA-pattern recognition system. C-ANCA and P-ANCA samples were selected from patients with ANCA-associated vasculitis (AAV).
Jan Damoiseaux, Kathleen Mallet, Mia Vaessen, Jos Austen, Jan Willem Cohen Tervaert   +4 more
doaj   +1 more source

ANCA-associated vasculitis [PDF]

Clinical Medicine, 2017
The vasculitides are a heterogeneous group of conditions typified by their ability to cause vessel inflammation with or without necrosis. They present with a wide variety of signs and symptoms and, if left untreated, carry a significant burden of mortality and morbidity.
Yates, Max, Watts, Richard
openaire   +4 more sources

Association of antineutrophil cytoplasmic antibody (ANCA) specificity with the demographic and clinical characteristics of patients with ANCA-associated vasculitides [PDF]

, 2022
Introduction Antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis (AAV) is characterized by the presence of proteinase-3(PR3) or myeloperoxidase(MPO) ANCA. In over 90% of cases, PR3-ANCA are associated with GPA. However, they are also rarely
Masiak, Anna, Jakuszko, Katarzyna, Brzosko, Iwona, Kur-Zalewska, Joanna, Storoniak, Hanna, Hawrot-Kawecka, Anna, Kucharz, Eugeniusz J., Wisłowska, Małgorzata, Madej, Marta, Głuszko, Piotr, Jeleniewicz, Radosław, Wójcik, Krzysztof, Marta Madej, Piotr Głuszko, Radosław Jeleniewicz, Hanna Storoniak, Anna Masiak, Eugeniusz J. Kucharz, for POLVAS consortium, Iwona Brzosko, Krzysztof Wójcik, Joanna Kur-Zalewska, Katarzyna Jakuszko, Anna Hawrot-Kawecka, Małgorzata Wisłowska   +23 more
core   +1 more source

A case report: Diagnosis and treatment of idiopathic hypertrophic pachymeningitis

Ibrain, Volume 11, Issue 1, Page 112-116, Spring 2025.
We reported a case of idiopathic hypertrophic dura meningitis diagnosed in our hospital. The patient repeatedly suffered from headaches, followed by blurred vision in the right eye. During this period, multiple sclerosis was considered for diagnosis, and it improved after hormone treatment.
Zhong Luo, Piao Cao, Jing‐Qing Xu, Rong Yan, Jian Wang, Tao Liang, Ya Chen, Zu‐Cai Xu   +7 more
wiley   +1 more source

ANCA-negative ANCA-associated vasculitis: pitfalls of the ‘vasculitis screen’

Clinical Medicine, 2023
Despite its recognition as an 'ANCA-associated vasculitis' (AAV), eosinophilic granulomatosis with polyangiitis (EGPA) is ANCA negative in up to 60% of cases. Herein, we report the case of a young man with a clinical syndrome highly suggestive of EGPA but with repeated negative ANCA serology, ultimately presenting with cardiac arrest before recognition
Cooke, Hannah, Wells, Matthew, Miller, Keith, Medford, Andrew R L, Patel, Sam   +4 more
openaire   +2 more sources