Results 41 to 50 of about 143,542 (269)

Race and Household Income are Associated with Disease Outcomes in Pediatric Patients with ANCA‐associated Vasculitis Hospitalized in the United States

open access: yesArthritis Care &Research, Accepted Article.
Objectives Race and household income impact outcomes in patients with rheumatic conditions; however, their role in pediatric anti‐neutrophil cytoplasmic antibody (ANCA)‐associated vasculitis (AAV) remains poorly understood. We aimed to evaluate whether race/ethnicity and household income are associated with severe AAV disease and renal outcomes among ...
Roberto Alejandro Valdovinos   +2 more
wiley   +1 more source

The Cognitive Triad Inventory (CTI) psychometric properties on a Romanian sample

open access: yesBMC Psychology
Background This study aims to develop the Romanian version of the Cognitive Triad Inventory (CTI) by documenting the Romanian translation of the instrument items and its psychometric characteristics. We were concerned with the items’ adaptation, analyzed
Anca -Monica Puia   +2 more
doaj   +1 more source

Exploring ANCA Pathogenicity in Ulcerative Colitis: A Case Report Highlighting the Risk of Progression to ANCA-Associated Vasculitis

open access: yesEuropean Journal of Case Reports in Internal Medicine
This case report addresses the association between ulcerative colitis and ANCA vasculitis-associated alveolar hemorrhage. A 20-year-old African woman with a history of ulcerative colitis with high PR3-ANCAs titer presented to the emergency department for
Abir Hamid   +2 more
doaj   +1 more source

Hypocomplementemia is associated with more severe renal disease and worse renal outcomes in patients with ANCA-associated vasculitis: a retrospective cohort study

open access: yesRenal Failure, 2020
Background The complement system has been recently proposed to play an important role in the pathogenesis of ANCA-associated vasculitis (AAV). This study evaluated the value of serum and kidney deposited C3 in predicting renal outcomes in AAV.
Aglaia Chalkia   +8 more
doaj   +1 more source

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

open access: yesAdvanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao   +16 more
wiley   +1 more source

The planktonic food web in the Gulf of Naples based on the analysis of carbon and nitrogen stable isotope ratios

open access: yesMarine Ecology, EarlyView., 2023
Abstract Plankton play a key role in marine food webs by producing and transferring organic matter and energy to higher trophic levels. To define the trophic structure and interactions within the planktonic communities in the Gulf of Naples, we determined carbon and nitrogen stable isotope ratios in particulate organic matter (POM, <20 μm ...
Louise Merquiol   +2 more
wiley   +1 more source

Infective endocarditis with antineutrophil cytoplasmic antibody: report of 13 cases and literature review.

open access: yesPLoS ONE, 2014
ObjectiveChronic infections tend to induce the production of antineutrophil cytoplasmic antibody (ANCA). Infective endocarditis (IE) has been reported to exhibit positive ANCA tests and to mimic ANCA-associated vasculitis, which may lead to a ...
Chun-Mei Ying   +3 more
doaj   +1 more source

Optimal management of Cogan’s syndrome: a multidisciplinary approach [PDF]

open access: yes, 2017
Cogan's syndrome (CS) is a rare disorder characterized by nonsyphilitic interstitial keratitis (IK) and audio-vestibular symptoms. CS affects mainly young Caucasian adults, mostly during their first three decades of age, and may develop into typical and ...
D'Aguanno, Vittorio   +3 more
core   +1 more source

Efficacy and Safety of Subcutaneous Efgartigimod PH20 in Adults With Primary Immune Thrombocytopenia (ADVANCE SC): A Multicenter, Randomized, Double‐Blinded, Placebo‐Controlled, Phase 3 Trial

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT Primary autoimmune thrombocytopenia (ITP) is characterized by thrombocytopenia, bleeding, and reduced health‐related quality of life. In the Phase 3 ADVANCE IV study, intravenous efgartigimod induced significant platelet count responses versus placebo in patients with chronic ITP. ADVANCE SC, a Phase 3, multicenter, randomized, double‐blinded,
Nichola Cooper   +546 more
wiley   +1 more source

Different Types of ANCA Determine Different Clinical Phenotypes and Outcome in ANCA-Associated Vasculitis (AAV)

open access: yesFrontiers in Medicine, 2022
AimAccumulating evidence supports the use of antineutrophil cytoplasmic antibody (ANCA) type to classify different clinical entities. We aimed to evaluate whether the presence and type of ANCA determine different diseases, based on clinical phenotypes ...
Kostas Bantis   +8 more
doaj   +1 more source

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