Results 31 to 40 of about 11,236,914 (284)
Collective dynamics differentiates functional divergence in protein evolution. [PDF]
PLoS Computational Biology, 2012 Protein evolution is most commonly studied by analyzing related protein sequences and generating ancestral sequences through Bayesian and Maximum Likelihood methods, and/or by resurrecting ancestral proteins in the lab and performing ligand binding ...
Tyler J Glembo +4 more
doaj +1 more source
iScience, 2023 Summary: Modern Japanese people have two major ancestral populations: indigenous Jomon hunter-gatherers and continental East Asian farmers. To determine the formation process of the current Japanese population, we developed a detection method for ...
Yusuke Watanabe, Jun Ohashi
doaj +1 more source
La profondeur des souches ancestrales au Québec, une mesure de la régionalité de la population
Espace populations sociétés, 2011 The ancestral roots of a population usually refer to the paternal lines, due to the transmission of surnames from one generation to another. However, paternal lines reach only a portion of the ancestors, whose relative importance diminishes as we go back
Marc Tremblay
doaj +1 more source
Reconstruction of ancestral protein sequences and its applications
BMC Evolutionary Biology, 2004 Background Modern-day proteins were selected during long evolutionary history as descendants of ancient life forms. In silico reconstruction of such ancestral protein sequences facilitates our understanding of evolutionary processes, protein ...
Grishin Nick V, Pei Jimin, Cai Wei
doaj +1 more source
A PCA-based method for ancestral informative markers selection in structured populations [PDF]
Science in China Series C: Life Sciences, 2009 Identification of population structure can help trace population histories and identify disease genes. Structured association (SA) is a commonly used approach for population structure identification and association mapping. A major issue with SA is that its performance greatly depends on the informativeness and the numbers of ancestral informative ...
Feng, Zhang, Lei, Zhang, Hong-Wen, Deng
openaire +2 more sources
PLoS ONE, 2013 The bacterial genomes of Thermotoga species show evidence of significant interdomain horizontal gene transfer from the Archaea. Members of this genus acquired many genes from the Thermococcales, which grow at higher temperatures than Thermotoga species ...
Nicholas C Butzin +5 more
doaj +1 more source
Parsimonious reconstruction of network evolution
Algorithms for Molecular Biology, 2012 Background Understanding the evolution of biological networks can provide insight into how their modular structure arises and how they are affected by environmental changes.
Patro Rob +5 more
doaj +1 more source
A new method of inference of ancestral nucleotide and amino acid sequences. [PDF]
Genetics, 1995 Abstract A statistical method was developed for reconstructing the nucleotide or amino acid sequences of extinct ancestors, given the phylogeny and sequences of the extant species. A model of nucleotide or amino acid substitution was employed to analyze data of the present-day sequences, and maximum likelihood estimates of parameters ...
Z, Yang, S, Kumar, M, Nei
openaire +2 more sources
Greedy selection of species for ancestral state reconstruction on phylogenies: elimination is better than insertion. [PDF]
PLoS ONE, 2010 Accurate reconstruction of ancestral character states on a phylogeny is crucial in many genomics studies. We study how to select species to achieve the best reconstruction of ancestral character states on a phylogeny.
Guoliang Li, Jian Ma, Louxin Zhang
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider +15 more
wiley +1 more source