Results 61 to 70 of about 11,236,914 (284)

Dispersed emergence and protracted domestication of polyploid wheat uncovered by mosaic ancestral haploblock inference

Nature Communications, 2022
The contribution of ancient haplotypes to domestication is largely unknown. Here, the authors develop an ancestral genomic haploblock dissection method to generate a mosaic pan-ancestry genomic map and reveal that the domesticated polyploidy wheat ...
Zihao Wang, Wenxi Wang, Xiaoming Xie, Yongfa Wang, Zhengzhao Yang, Huiru Peng, Mingming Xin, Yingyin Yao, Zhaorong Hu, Jie Liu, Zhenqi Su, Chaojie Xie, Baoyun Li, Zhongfu Ni, Qixin Sun, Weilong Guo   +15 more
doaj   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

Using ancestral state reconstruction methods for onomasiological reconstruction in multilingual word lists [PDF]

Language Dynamics and Change, 2018
AbstractCurrent efforts in computational historical linguistics are predominantly concerned with phylogenetic inference. Methods for ancestral state reconstruction have only been applied sporadically. In contrast to phylogenetic algorithms, automatic reconstruction methods presuppose phylogenetic information in order to explain what has evolved when ...
Jäger, Gerhard, List, Johann-Mattis
openaire   +4 more sources

GAD65 Antibody ELISA With Extended Reportable Range: Validation and Guidance for Neurological Practice

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To (1) validate GAD65‐ELISA detection and quantification for type 1 diabetes mellitus and autoimmune neurological diagnoses, (2) correlate ELISA results (reference range < 5 IU/mL) with established radioimmunoprecipitation assay (RIA; ≤ 0.02 nmol/L), and (3) define ELISA clinical utility and pitfalls.
Andrew McKeon, Dana Olofson, Diana Anissian, Divyanshu Dubey, Eoin P. Flanagan, Max C. Herman, Sarosh R. Irani, Daniel H. Lachance, Maria A. Willrich, Sean Pittock, John R. Mills, Anastasia Zekeridou   +11 more
wiley   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source

Transgenerational Inheritance and Systemic Racism in America

Psychiatric Research and Clinical Practice, 2023
Objective It is well established that personal experiences of trauma, adversity, and discrimination can “get under the skin” and increase risk for a whole host of negative mental and physical health outcomes. The aim of this article is to review emerging
Joan Kaufman, Maria Khan, Jennifer Shepard Payne, Julia Mancini, Yvonne Summers White   +4 more
doaj   +1 more source

Single-character insertion–deletion model preserves long indels in ancestral sequence reconstruction

BMC Bioinformatics
Insertions and deletions (indels) play a significant role in genome evolution across species. Realistic modelling of indel evolution is challenging and is still an open research question.
Gholamhossein Jowkar, Jūlija Pečerska, Manuel Gil, Maria Anisimova   +3 more
doaj   +1 more source

MOGAD Is the Most Common Cause of Isolated Optic Neuritis in Children

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives The study aimed to characterize the clinical features, etiologies, and outcomes of isolated, first‐time pediatric ON in the post‐MOG‐IgG era. Methods This was a single‐center retrospective cohort study at Texas Children's Hospital of patients diagnosed with first‐time ON between 2018–2024, with follow‐up data collected through 2025.
Chaitanya Aduru, Akansha Chandrasekar, Kyla Blasingame, Jonathan Rosen, Jesse M. Levine, Karla Salazar, Madhuri Chilakapati, Rod Foroozan, Victoria Hardwick, Jonathan M. Yarimi, Nikita Shukla, Timothy E. Lotze, Kristen S. Fisher, Alexander J. Sandweiss   +13 more
wiley   +1 more source

Portifólio: Conselho Ancestral Willka Yaku

, 2023
Translation: Works included:1. Memoirs of Grandmother Water2. Grandmother Water's MandatesTraducción: Obras incluídas:1. Memorias de la Abuela Agua2. Mandatos de la Abuela AguaTradução: Obras incluídas: 1. Memórias da Avó Água2.
Yaku, Conselho Ancestral Willka
core   +1 more source

Re(cover)ing Revelations: Formulating Black Ancestral Text Analysis in Education Research

International Journal of Qualitative Methods
Traditional research on Blackness in education often renders Black people nonhuman (Wynter, 1994). In this article, we formulate Black ancestral text analysis , a qualitative research method in which Black thinkers excavate the ancestral knowledges ...
Latoya M. Teague, Mariama N. Nagbe
doaj   +1 more source