Results 71 to 80 of about 13,467,690 (274)

Au temps passé d’une comptine : application d’outils phylogénétiques pour reconstruire une tradition orale

open access: yesStrenae, 2020
One problem in the study of children's games is reconstructing their history and ancestral forms. Here I will borrow tools from evolutionary biology for this purpose.
Julien d'Huy
doaj   +1 more source

Ancestral-Character Evolution of Bioluminescence in Sixteen Major Lineages of Fishes.

open access: yes, 2016
Bayesian ancestral-character-states reconstruction of bioluminescence across a distribution of 500 trees that resulted from the Bayesian inference of divergence times. Each rectangle includes 500 individual reconstructions across this distribution of 500
Matthew P. Davis (309819)   +2 more
core   +1 more source

ProCARs: Progressive Reconstruction of Ancestral Gene Orders [PDF]

open access: yes, 2014
International audienceBACKGROUND:In the context of ancestral gene order reconstruction from extant genomes, there exist two main computational approaches: rearrangement-based, and homology-based methods.
Jean-Stéphane Varré   +7 more
core   +1 more source

Validation of a Cellular Imaging‐Based Method as a Potential Biomarker for SPG4 Hereditary Spastic Paraplegia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Hereditary Spastic Paraplegia (HSP) comprises a group of rare genetic diseases characterized by length‐dependent axonal degeneration of the corticospinal tracts and dorsal columns, whose main clinical feature is spastic gait. Pathogenic variants in the SPG4 gene cause Spastic Paraplegia Type 4 (SPG4‐HSP), the most common form of HSP.
Gaia Fattorini   +12 more
wiley   +1 more source

One origin for metallo-β-lactamase activity, or two? An investigation assessing a diverse set of reconstructed ancestral sequences based on a sample of phylogenetic trees [PDF]

open access: yes, 2014
This work was supported by BBSRC (grant BB/F016778/1)Bacteria use metallo-β-lactamase enzymes to hydrolyse lactam rings found in many antibiotics, rendering them ineffective.
Barker, Daniel   +8 more
core   +1 more source

White Matter and Perivascular Imaging Changes in Alzheimer's Disease and Cerebral Amyloid Angiopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Peak‐width of skeletonized mean diffusivity (PSMD) and diffusion tensor imaging–analysis along the perivascular space (DTI‐ALPS), reflecting white matter integrity and glymphatic function, are altered in Alzheimer's disease (AD).
Debina Laishram   +3 more
wiley   +1 more source

A Causality Perspective of Genomic Breed Composition for Composite Animals

open access: yesFrontiers in Genetics, 2020
Genomic breed composition (GBC) of an individual animal refers to the partition of its genome according to the inheritance from its ancestors or ancestral breeds.
Xiao-Lin Wu   +13 more
doaj   +1 more source

Changes in post-marital residence precede changes In descent systems in Austronesian societies [PDF]

open access: yes, 2007
Descent systems express how a society organises kinship relationships. Inheritance of resources as well as rights and obligations can be traced patrilineally, matrilineally, a combination of both, or in a cognatic/bilateral fashion.
Jordan, Fiona M   +3 more
core  

Axial Function Reflects Global Severity in Inherited Ataxias: The Upright Stability Score in Ambulatory Friedreich vs. Spinocerebellar Ataxia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Inherited ataxias are clinically diverse neurodegenerative diseases, complicating the choice of outcome measures for trials. In spinocerebellar ataxia (SCA), regulatory concerns about the Scale for the Assessment and Rating of Ataxia (SARA) caused a shift toward functional SARA (f‐SARA), contributing to pivotal trial failure.
Christian Rummey   +52 more
wiley   +1 more source

Charge‐Reversed Lipid Nanoparticles Enable Encapsulation of Pt2L4 Nanocages for In vivo Anti‐Cancer Treatment

open access: yesAdvanced Materials, EarlyView.
Charge‐reversed lipid nanoparticles (revLNPs) enable efficient encapsulation and delivery of cationic Pt2L4 nanocages. Encapsulation preserves potent anticancer activity while improving circulation, reducing vascular leakage, and promoting favorable biodistribution in vivo.
Renzo A. Knol   +16 more
wiley   +1 more source

Home - About - Disclaimer - Privacy