Results 81 to 90 of about 101,127 (289)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Long-Term PIT and T-Bar Anchor Tag Retention Rates in Adult Muskellunge
, 2011 Mark-recapture studies require knowledge of tag retention rates specific to tag types, fish species and size, and study duration. We determined the probability of tag loss for passive integrated transponder (PIT) tags implanted into dorsal musculature ...
Rude, Neil P +7 more
core +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
The Effect of Anchor Tenant Loss on Shopping Center Rents [PDF]
This paper examines the effect that the loss of a shopping center anchor tenant has on the rental rates of the remaining tenants. Using data from smaller and moderately sized centers located in Florida and Georgia, two alternative regression procedures ...
Dean H. Gatzlaff +2 more
core
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Anchor Loss Reduction in Micro-Electro Mechanical Systems Flexural Beam Resonators Using Trench Hole Array Reflectors. [PDF]
Micromachines (Basel), 2023 Kazemi M, Nabavi S, Gratuze M, Nabki F.
europepmc +1 more source
Drifting Without an Anchor: How Pitch Accents Withstand Vowel Loss
Language and Speech, 2015 We offer an analysis of the influence exerted by segmental rules on the suprasegmental structure in the dialect of Ipiros Greek (IG). In particular we investigated how vowel deletion (VD) affects the phonetic realization of the L*+H pitch accent. Our data empirically establish that the H tone aligns much earlier when VD applies than when it does not ...
Baltazani, M, Kainada, E
openaire +2 more sources
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
Visualization of Flap Length Effects on the Keying Process of Plate Anchors in Transparent Soil
Journal of Marine Science and EngineeringSuction embedded plate anchors (SEPLAs) are widely used in offshore engineering, but their keying process is often accompanied by embedment loss, which reduces the holding capacity.
Chunhui Zhang +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source